Abstract:Objective: To analysis the application effect of spinal epidural anesthesia combined continuous epidural anesthesia in total hysterectomy, and to provide reference for clinical anesthesia. methods: 86 patients with total hysterectomy admitted in our hospital from December 2013 to February 2015 were selected. All the patients were randomly average divided into anesthesia group and epidural anesthesia group. Anesthesia group patients were taken anesthesia of combined spinal epidural anesthesia, epidural anesthesia group patients were taken anesthesia of continuous epidural anesthesia, the mean arterial pressure and heart rate were recorded, anesthetic effect of patients were compared. Results: Joint anesthesia onset time of anesthesia was significantly shorter than the epidural anesthesia group, P <0.05, two groups of patients no significant difference in operative time, the amount of anesthetic in anesthesia group was significantly lower than epidural anesthesia group, P <0.05. Different time, anesthesia group MAP, HR and oxygen saturation smooth change, the change was significantly lower than the epidural anesthesia group, P <0.05. The total fine rate observed on Narcotic was significantly higher than epidural anesthesia group, P <0.05, a muscle relaxant anesthesia group was significantly better than the epidural anesthesia group, P <0.05, two groups of patients with adverse events was no significant difference, P> 0.05. Conclusion: The method of spinal epidural anesthesia combined continuous epidural anesthesia in total hysterectomy is simple, safe and effective.