Evaluation of Curative Effect of Improved Hysteroscopy Combined withLaparoscopy in Treatment of Tubal Infertility Stress Factors and its Effects on Inflammatory Factors
WANG Gaiqin, et al
The Third Hospital of PLA, Shaanxi Baoji 721004, China
Abstract：Objective: To study improved hysteroscopy combined with aparoscopy in treatment of tubal infertility stress factors and its effects on inflammatory factors. Methods: 80 patients of tubal infertility who received therapy from August 2014 to August 2015 in our hospital were selected as research objects. The control group was treated with tradition hysteroscopy combined with aparoscopy, while the observation group was treated with Improved hysteroscopy combined with aparoscopy, Then The stress level of adrenaline (E), cortisol(Cor), Thyroid stimulating hormone(TSH), inflammatory factors interleukin-2(IL-2), interleukin-6(IL-6), interleukin-8(IL-8), C reactive protein (CRP), treatment efficacy before and after treatment two groups of patients were compared.Results: After treatment, tubal patency rate, intrauterine pregnancy rate in observation group was than the control group, ectopic pregnancy rate in observation group was less than the control group[92.50%(37/40)vs75.00%(30/40),95.00%(38/40)vs75.00%(30/40),5.00%(2/40)vs22.50%(9/40)] (P＜0.05); E,or in observation group was less than the control group, TSH in observation group was than the control group[(96.16±10.25)ng/ml vs(152.17±16.03)ng/ml、(146.86±18.97)ng/ml vs(236.16±23.17)ng/ml、(3.10±0.50)mU/L vs(1.82±0.32)mU/L] (P＜0.05); IL-2、IL-6、IL-8、CRP in observation group was less than the control group[(17.80±2.21)pg/ml vs(29.07±4.70)pg/ml、(43.21±5.86)pg/ml vs(54.26±6.23)pg/ml、(183.25±34.20)pg/ml vs(213.97±50.65)pg/ml、(5.03±0.81)pg/ml vs(6.12±0.90)pg/ml] (P＜0.05); The total effective rate of observation group was statistically higher than that in the control group95.00%(38/40)vs75.00%(30/40)(P＜0.05). Conclusion:To improve the effect of hysteroscopy and laparoscopy in the diagnosis and treatment is well for tubal infertility, which can reduce the expression of stress factors and inflammatory factors, which is beneficial to the prognosis of the patients.
王改琴, 党淼, 耿俐, 王晓宁, 崔琨. 改进宫腹腔镜诊治输卵管性不孕症的疗效评价及对应激因子与炎症因子的影响[J]. 河北医学, 2017, 23(4): 539-543.
WANG Gaiqin, et al. Evaluation of Curative Effect of Improved Hysteroscopy Combined withLaparoscopy in Treatment of Tubal Infertility Stress Factors and its Effects on Inflammatory Factors. 河北医学, 2017, 23(4): 539-543.
[1] 蒋荣英,刘洁冰.腹腔镜在治疗输卵管性不孕症中的作用[J].当代医学,2013,16:7-8. [2] Singh S, Bhandari S, Agarwal P, et al. Chlamydia antibody testing helps in identifying females with possible tubal factor infertility[J].Int Reprod Biomed (Yazd),2016,14(3):187~192. [3] 江依群,冯爱辉,周晔.宫腹腔镜联合下输卵管疏通术治疗不孕症的临床分析[J].实用医学杂志,2013,02:248-250. [4] 陈璐,李丹,刘爱民.输卵管性不孕症的诊疗进展[J].武警后勤学院学报(医学版),2013,05:458-460. [5] 王艳蕊.宫腹腔镜联合术诊治输卵管性不孕症的疗效分析[J].当代医学,2013,25:65-66. [6] Lazer T, Meltzer S, Saar-Ryss B, et al. The place of selective hysterosalpingography and tubal canalization among sub-fertile patients diagnosed with proximal tubal occlusion[J].Arch Gynecol Obstet. 2016;293(5):1107-1111. [7] 巩春梅.宫腹腔镜联合治疗38例输卵管性不孕症的疗效分析[J].中国现代医生,2013,08:25-26. [8] Sharma JB, Sneha J, Singh UB, et al. Comparative Study of Laparoscopic Abdominopelvic and Fallopian Tube Findings Before and After Antitubercular Therapy in Female Genital Tuberculosis With Infertility[J].J Minim Invasive Gynecol. 2016;23(2):215-222. [9] 孔元蓉,叶颖斐.宫腹腔镜联合治疗输卵管性不孕症的临床分析[J].河北医药,2013,13:1967-1969. [10] González-Fernández R, Hernández J, Martín-Vasallo P, et al. Expression Levels of the Oxidative Stress Response Gene ALDH3A2 in Granulosa-Lutein Cells Are Related to Female Age and Infertility Diagnosis[J].Reprod Sci,2016,23(5):604~609. [11] 李红苓,应小燕.宫、腹腔镜联合诊治输卵管性不孕症改进手术方法后的妊娠结局[J].中国微创外科杂志,2016,03:217-220. [12] Check JH. A practical approach to diagnosing and treating infertility by the generalist in obstetrics and gynecology[J].Clin Exp Obstet Gynecol,2015,42(4):405~410. [13] Meng FL,Lu JQ. Clinical effect of hysteroscopy combined with laparoscopy in the treatment of tubal infertility[J].Chin Matern Child Health Care,2015,30(02):317-319. [14] Kasia JM, Ngowa JD, Mimboe YS, et al. Laparoscopic Fimbrioplasty and Neosalpingostomy in Female Infertility: A Review of 402 Cases at the Gynecological Endoscopic Surgery and Human Reproductive Teaching Hospital in Yaoundé-Cameroon[J].Reprod Infertil,2016,17(2):104~109. [15] Nsonwu-Anyanwu AC, Charles-Davies MA, Bello FA, et al. Cytokine profile in Nigerians with tubal infertility[J].Cent Eur Immunol,2016,41(1):101~106. [16] Groszmann YS, Benacerraf BR. Complete evaluation of anatomy and morphology of the infertile patient in a single visit; the modern infertility pelvic ultrasound examination[J].Fertil Steril,2016,105(6):1381~1393. [17] 郑真真,冯晓,史小菲,等. 宫腹腔镜联合诊治输卵管性不孕症的价值[J].现代妇产科进展,2014,05:380-382. [18] Zebitay AG, Tutumlu M, Verit FF, et al. A comparative analysis of arterial blood flow in unexplained infertility, tubal infertility and fertile groups[J].Gynecol Endocrinol,2016,32(6):442~445. [19] 李小燕,向佳.经阴道宫腔镜手术与腹腔镜手术治疗输卵管妊娠的手术结局及对患者炎性应激反应的影响[J].中国医学装备,2016,04:85-88. [20] 白雪,李冬梅,郝妍, 等.输卵管通液术前后患者血清中炎性因子的表达及意义[J].中国妇幼保健,2015,11:1752-1754.
2017, Vol. 23 
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