Abstract：Objective: To explore the risk factors of axillary lymph node metastasis in breast cancer patients and compare the diagnostic efficacy of X-ray and CT examinations.Methods: A total of 112 breast cancer patients treated in our hospital from January 2021 to May 2023 were selected. Differences in clinical data between patients with and without axillary lymph node metastasis were analyzed. The diagnostic value of X-ray and CT examinations for axillary lymph node metastasis was also assessed. Results: Among the 112 patients, 32 had axillary lymph node metastasis, lymph node metastasis rate was 28.57%. The proportion of patients with axillary lymph node metastasis with low differentiation, invasive cancer, vascular infiltration, tumor diameter ≥5cm, and Ki-67 expression ≥14% were 68.75%, 90.63%, 28.13%, 31.25%, and 84.38%, respectively, which were significantly higher than those without axillary lymph node metastasis (P<0.05). Logistic regression analysis showed that differentiation degree, focus tissue type, vascular invasion, Ki-67 expression were the influencing factors of axillary lymph node metastasis in breast cancer patients (P<0.05). The consistency between X-ray diagnosis of axillary lymph node metastasis and pathological results was poor, with a Kappa value of 0.500 and P<0.05. The consistency between CT diagnosis of axillary lymph node metastasis and pathological results was good, with a Kappa value of 0.825 and P<0.05. The sensitivity, accuracy, and negative predictive values of CT in diagnosing axillary lymph node metastasis were 92.86%, 87.50%, and 95.00%, respectively, which were significantly higher than those of X-ray examination (P<0.05). Conclusion: The occurrence of axillary lymph node metastasis in breast cancer patients is influenced by differentiation degree, lesion tissue type, vascular invasion, and Ki-67 expression. Compared to X-ray, CT demonstrates higher diagnostic value for axillary lymph node metastasis.
王浩宇, 石文达, 赵晓彬, 崔志新. 乳腺癌患者腋窝淋巴结转移的危险因素及行X线摄影与CT检查的诊断效能分析[J]. 河北医学, 2024, 30(3): 506-510.
WANG Haoyu, SHI Wenda, ZHAO Xiaobin, et al. Risk Factors for Axillary Lymph Node Metastasis in Breast Cancer Patients and Comparative Diagnostic Efficacy of X-ray Imaging and CT Scans. HeBei Med, 2024, 30(3): 506-510.
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2024, Vol. 30 
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