Analysis of the Relationship between the Changes of Coagulation Index and the Prognosis of Patients with Pulmonary Infection Caused by Multiple Injuries and Acute Respiratory Distress Syndrome
GAN Kui, et al
Changsha Third Hospital, Hunan Changsha 410035, China
Abstract：Objective: To explore the relationship between the changes of coagulation index and the prognosis of patients with pulmonary infection caused by multiple injuries and acute respiratory distress syndrome. Methods: From August 2019 to December 2020, a total of 121 patients with multiple injuries were enrolled, and complete demographic characteristics and clinical laboratory baseline data were collected at the time of enrollment. According to the Simple Clinical Pulmonary Infection Score (sCPIS), the patients were divided into lung infection group (n=62) and non-pulmonary infection group (n=59). According to the 28-day mortality rate, patients with lung infection caused by multiple injuries and ARDS were divided into survival group (n=31) and death group (n=31). One-way analysis of variance assesses the presence or absence of lung infection and the difference between the demographic characteristics of the survival group and the death group and the clinical laboratory baseline. Logisitic regression and ROC curve analyze the SOFA score of patients with lung infection caused by multiple injuries and ARDS, The predictive value of PT, FDP, DD and ICU stay. Results: There were 121 patients with multiple injuries and 62 patients with pulmonary infection caused by multiple injuries and ARDS. The SOFA score, APTT, INR, AT-Ⅲ, ICU stay and 28-day mortality of patients with lung infection were higher than those of non-pulmonary infections, and SOFA scores, PT, FDP, PT, FDP, pulmonary infection caused by multiple injuries and ARDS death group, DD and higher than survival group (P<0.01). Logisitic regression and ROC curve analysis PT is a prognostic factor for patients with lung infection caused by multiple injuries and ARDS. The ROC curve area is 0.737, and the difference is statistically significant (P<0.05). Conclusion: This study showed that the coagulation index of the lung infection caused by multiple injuries and ARDS death group was higher than that of the survival group. Early warning values.
干魁, 李子文, 李国军, 杨骞. 凝血指标变化与多发伤所致肺部感染并急性呼吸窘迫综合征患者预后关系分析[J]. 河北医学, 2023, 29(12): 2072-2076.
GAN Kui, et al. Analysis of the Relationship between the Changes of Coagulation Index and the Prognosis of Patients with Pulmonary Infection Caused by Multiple Injuries and Acute Respiratory Distress Syndrome. HeBei Med, 2023, 29(12): 2072-2076.
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2023, Vol. 29 
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