Effectiveness of Balloon Dilatation Angioplasty in the Treatment of Atherosclerotic Intracranial Artery Stenosis Combined with Acute Cerebral Infarction and Its Effect on Quality of Life
CHENG Fei, YANG Hui, ZHOU Shiling, et al
Qionghai People's Hospital, Hainan Qionghai 571400, China
Abstract：Objective: To study the surgical effect and quality of life of balloon dilated angioplasty in the treatment of atherosclerotic intracranial artery stenosis combined with acute cerebral infarction. Methods: A total of 35 patients with atherosclerotic intracranial artery stenosis complicated with acute cerebral infarction who were treated with balloon dilatation angioplasty in our hospital from October 2021 to December 2022 were selected as the balloon dilatation group, another 35 patients with atherosclerotic intracranial artery stenosis complicated with acute cerebral infarction who were treated with intravenous thrombolytic therapy were randomly selected as the intravenous thrombolytic group, ang then 35 patients with atherosclerotic intracranial artery stenosis complicated with acute cerebral infarction who were treated with internal medicine conservative treatment were selected as conservative treatment group. The therapeutic effect, National Institutes of Health Stroke Scale (NIHSS) score, modified Rankin Scale (MRS) score, cerebral blood perfusion index, and quality of life of the three groups were compared. Results: The total effective rate of balloon expansion group was higher than that of intravenous thrombolysis group and conservative treatment group (P<0.05), and the total effective rate of intravenous thrombolysis group was higher than that of conservative treatment group (P<0.05). There was no significant difference in NIHSS score and MRS Score between the three groups before treatment (P>0.05). After treatment, NIHSS score and MRS Score of the three groups were lower than those before treatment, and the reduction rate of balloon dilation group was greater than that of intravenous thrombolysis group and conservative treatment group (P<0.05). The reduction rate of intravenous thrombolysis group was greater than that of conservative treatment group (P<0.05). Comparison of regional cerebral blood flow velocity (rCBF), mean transit time (MTT) and regional cerebral blood volume (rCBV) among the three groups before treatment showed no statistical significance (P＞0.05), while rCBF and rCBV were higher in the balloon expansion group than in the intravenous thrombolysis group and the conservative treatment group after treatment (P＞0.05). The rCBF and rCBV of the three groups after treatment were higher than those before treatment, and the magnitude of increase in the balloon dilatation group was greater than that of the intravenous thrombolysis group and the conservative treatment group (P<0.05), and the magnitude of increase in the intravenous thrombolysis group was greater than that of the conservative treatment group (P<0.05), the MTT of the three groups after treatment was lower than that of the preoperative group, and the magnitude of decrease in the balloon dilatation group was greater than that of the intravenous thrombolysis group and the conservative treatment group (P<0.05). group (P<0.05), and the decrease in the intravenous thrombolysis group was greater than the MTT in the conservative treatment group (P<0.05). After treatment, the scores of physiology, psychology, social relations, subjective quality of life, and subjective health status in balloon dilation group were higher than those in intravenous thrombolytic group and conservative treatment group (P<0.05), the scores of intravenous thrombolytic group were higher than those in conservative treatment group (P<0.05), and the scores of environmental field in balloon dilation group were higher than those in intravenous thrombolytic group and conservative treatment group (P<0.05). There was no significant difference in environmental field scores between the intravenous thrombolytic group and the conservative treatment group (P>0.05). Conclusion: Balloon dilated angioplasty for atherosclerotic intracranial artery stenosis combined with acute cerebral infarction can significantly improve the neurological function and cerebral blood perfusion index, with higher quality of life.
程飞, 杨辉, 周世玲, 赵航. 球囊扩张血管成形术治疗动脉粥样硬化性颅内动脉狭窄合并急性脑梗死的效果及对生活质量的影响[J]. 河北医学, 2023, 29(10): 1692-1697.
CHENG Fei, YANG Hui, ZHOU Shiling, et al. Effectiveness of Balloon Dilatation Angioplasty in the Treatment of Atherosclerotic Intracranial Artery Stenosis Combined with Acute Cerebral Infarction and Its Effect on Quality of Life. HeBei Med, 2023, 29(10): 1692-1697.
2023, Vol. 29 
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