Analysis of Clinical Characteristics and Factors Associated with the Occurrence of Sarcopenia in Elderly Patients after Esophageal Squamous Carcinoma Surgery
WANG De’en, YANG Wei, WANG Weimin, et al
Huai'an First Hospital,Nanjing Medical University, Jiangsu Huai'an 223300, China
Abstract：Objective: To analyze the clinical characteristics and related factors of sarcopenia (SA) in elderly patients after esophageal squamous carcinoma surgery. Methods: A retrospective analysis was performed on the clinical data of 120 elderly patients with esophageal squamous carcinoma admitted to the hospital between March 2018 and October 2021. According to L3 skeletal muscle index (L3 SMI) and international diagnostic criteria for SA (male: L3 SMI ≤40.8cm2/m2, female: L3 SMI ≤34.9cm2/m2), the patients were divided into SA group (n=49) and non-SA group (n=71). Postoperative clinical characteristics of the two groups were recorded, and the influencing factors of SA were screened by logistic regression analysis. Results: There were statistically significant differences in general data [age, Karnofsky Performance Scale (KPS) score, body mass index (BMI), and serum prealbumin (PA)] between the two groups (P<0.05), but there was no statistically significant difference in the other clinical indexes (P>0.05). Logistic regression analysis showed that age, KPS score and BMI were influencing factors of SA. Conclusion: The occurrence of SA in elderly patients after esophageal squamous carcinoma surgery is related to multiple factors. Clinically, attention should be paid to the related factors of SA, timely and targeted intervention measures should be taken to reduce the incidence of postoperative SA.
王得恩, 杨薇, 汪为民, 张晰, 蒋超. 老年食管鳞癌术后患者肌少症发生临床特征及相关因素分析[J]. 河北医学, 2023, 29(4): 591-595.
WANG De’en, YANG Wei, WANG Weimin, et al. Analysis of Clinical Characteristics and Factors Associated with the Occurrence of Sarcopenia in Elderly Patients after Esophageal Squamous Carcinoma Surgery. HeBei Med, 2023, 29(4): 591-595.
2023, Vol. 29 
冀公网安备13080202000677号