2025年4月4日 星期五
首页        期刊介绍        编委会        投稿指南        期刊订阅        广告合作        联系我们        English
河北医学  2023, Vol. 29 Issue (1): 103-107    DOI: 10.3969/j.issn.1006-6233.2023.01.019
  临床研究 本期目录 | 过刊浏览 | 高级检索 |
多重炎症指数对川崎病患儿心血管并发症的预测价值
李方旺, 胡方启, 吴露依, 王利华, 饶军
安徽省安庆市立医院儿科, 安徽 安庆 246000
Predictive Value of Multiple Inflammatory Indices for Cardiovascular Complications in Children with Kawasaki Disease
LI Fangwang, HU Fangqi, WU Luyi, et al
Anqing Municipal Hospital, Anhui Anqing 246000, China
全文: PDF (1276 KB)   HTML (1 KB) 
输出: BibTeX | EndNote (RIS)      
摘要 目的: 探讨多重炎症指数对川崎病患儿心血管并发症的预测价值。方法: 连续性收集本院2020年1月至2022年5月收治为KD患儿127例为研究对象,根据MII中位数将其分为高MII组和低MII组。采用自制一般资料调查表收集患儿性别、年龄等人口学资料,通过电子病历系统获取患儿发热时间、结膜充血、淋巴结肿大等临床资料。对患儿进行为期 12 个月的心血管并发症为结局的随访。 结果: 高MII组和低MII组性别、发热时间、淋巴结肿大率比较差异无统计学意义(P>0.05),高MII组年龄、结膜充血率高于低MII组,差异具有统计学意义(P<0.05)。K-M生存曲线分析结果显示,高MII-1组、高MII-2组中位心血管并发症发生率分别为87.50%和90.63%,低MII-1组、低MII-2组中位心血管并发症发生率分别为76.19%和74.60%,两组比较差异具有统计学意义(χ2=10.680、10.860,P=0.001、0.001)。多因素分析显示,MII-1(OR=2.247,P<0.001)、MII-2(OR=2.134,P<0.001)是KD患儿发生心血管并发症的独立影响因素。ROC分析结果显示,当MII-1、MII-2分别取值784.64、21876.76时,对KD患儿随访12个月后发生心血管并发症达到最大预测效能,此时曲线下面积分别为0.680、0.726。结论: 多重炎症指数对于预测川崎病患儿心血管并发症有一定临床价值,值得临床推广应用。
服务
把本文推荐给朋友
加入我的书架
加入引用管理器
E-mail Alert
RSS
作者相关文章
关键词 多重炎症指数川崎病心血管并发症预测价值    
AbstractObjective: To explore the predictive value of multiple inflammatory indices for cardiovascular complications in children with Kawasaki disease. Methods: A total of 127 children with KD admitted to our hospital from January 2020 to May 2022 were continuously collected as the research subjects, and they were divided into high MII group and low MII group according to the median of MII. Demographic data such as gender and age were collected using self-made general information questionnaire, and clinical data such as fever time, conjunctival hyperemia, and lymphadenopathy were obtained through electronic medical record system. Children were followed up for 12 months with cardiovascular complications as the outcome. Results: There was no significant difference in gender, fever time, and lymph node enlargement rate between the high MII group and the low MII group (P>0.05). The age and conjunctival hyperemia rate in the high MII group were higher than those in the low MII group, and the differences were statistically significant (P<0.05). The results of the K-M survival curve analysis showed that the median cardiovascular complication rates were 87.50% and 90.63% in the high MII-1 and high MII-2 groups, respectively, and 76.19% and 74.60% in the low MII-1 and low MII-2 groups, respectively, with statistically significant differences between the two groups (χ2=10.680, 10.860 , P=0.001, 0.001). Multivariate analysis showed that MII-1 (OR=2.247, P<0.001) and MII-2 (OR=2.134, P<0.001) were independent influencing factors of cardiovascular complications in children with KD. The results of ROC analysis showed that when the values of MII-1 and MII-2 were 784.64 and 21876.76, respectively, the maximum predictive performance of cardiovascular complications in children with KD after 12 months of follow-up was achieved, and the areas under the curve were 0.680 and 0.726, respectively. Conclusion: Multiple inflammatory indices have certain clinical value in predicting cardiovascular complications in children with Kawasaki disease, and are worthy of clinical application
Key wordsMultiple inflammatory indices    Kawasaki disease    Cardiovascular complications    Predictive value
    
基金资助:2021年度安徽高校自然科学研究项目,(编号:KJ2021A1291)
引用本文:   
李方旺, 胡方启, 吴露依, 王利华, 饶军. 多重炎症指数对川崎病患儿心血管并发症的预测价值[J]. 河北医学, 2023, 29(1): 103-107.
LI Fangwang, HU Fangqi, WU Luyi, et al. Predictive Value of Multiple Inflammatory Indices for Cardiovascular Complications in Children with Kawasaki Disease. HeBei Med, 2023, 29(1): 103-107.
链接本文:  
http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2023.01.019     或     http://www.hbyxzzs.cn/CN/Y2023/V29/I1/103
冀ICP备2025106803号    冀公网安备13080202000786号
版权所有 © 2016 《河北医学》杂志社
本系统由北京玛格泰克科技发展有限公司设计开发