Abstract：Objective: To evaluate the effect of spermatic vein ligation on the total antioxidant capacity (TAC) of semen in patients with varicocele.Methods: Forty infertile male patients with varicocele and 40 healthy controls (control group) were admitted to our hospital for primary or secondary infertility. Patients with varicocele were divided into two groups: nonobvious palpation (GI) varicocele group (16 cases) and obvious palpation (GⅡ-Ⅲ) varicocele group (24 topics). All patients underwent microscopical ligation of the spermatic vein. The semen TAC level and sperm parameters of all patients were evaluated. The preoperative sperm quantity, sperm motility, sperm morphology, and semen TAC level were compared with the same parameters 3 ~ 6 months after spermatic vein ligation and the control group. Results: After spermatic vein ligation, the sperm count (preoperative 18.01±1.88, postoperative 24.20±7.60, P=0.040), motile sperm (preoperative 17.90±8.90, postoperative 23.90±7.90, P=0.001), NF (10.20±3.02 before operation, 19.30±7.05 after operation, P<0.001) and semen TAC level (2.52±0.28 before operation, 3.72±0.20 after operation, P=0.031) were higher than those before operation, and the difference was statistically significant (P<0.05); and compared with the control group after operation, sperm count (varicocele patients 24.20±7.60, control group 29.40±8.30, P=0.156), sperm motility (varicocele patients 23.90±7.90, control group 23.90±7.90) 30.50±8.00, P=0.465), NF (varicocele patients 19.30±7.05, control group 23.90±7.90, P=0.085) and semen TAC level (varicocele patients 3.72±0.20, control group 2.78±0.20, P=0.666), the difference was not statistically significant (P>0.05). However, according to the evaluation of the patients' varicocele grade, only patients with GII-III varicocele had NF before and after surgery (6.16±2.50 preoperatively, 10.00±6.41 postoperatively, P=0.040), TAC (preoperatively 6.16±2.50, P=0.040). 2.36±0.23, postoperative 2.66±0.15, P=0.040) level difference was statistically significant (P<0.05). When the patients were grouped according to semen parameters, there was a statistically significant difference in TAC levels in the oligospermia (OAT) group (2.46 ± 0.34 before surgery, 2.80 ± 0.19 after surgery, P=0.000). Conclusion: Spermatic vein ligation significantly improves the total antioxidant capacity of semen in patients with GII-III varicocele.
张俊杰, 杨阳, 罗旋, 杜业芳. 精索静脉结扎术对精索静脉曲张患者精子总抗氧化能力的影响[J]. 河北医学, 2022, 28(11): 1902-1905.
ZHANG Junjie, YANG Yang, LUO Xuan, et al. Effect of Spermatic Vein Ligation on Total Antioxidant Capacity of Sperms in Patients with Varicocele. HeBei Med, 2022, 28(11): 1902-1905.
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2022, Vol. 28 
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