Abstract：Objective: To explore the effect of aortic balloon counterpulsation (IABP) combined with percutaneous coronary intervention (PCI) in the treatment of acute myocardial infarction (AMI) patients on postoperative cardiac dysfunction.Methods: The general clinical data of 81 patients with AMI admitted to the hospital between August 2014 and April 2021 were retrospectively analyzed. Patients enrolled were grouped according to the treatment method. Those treated with PCI alone were included in the control group (n=39), and those treated with IABP combined PCI were included in the study group (n=42). The changes in cardiac function, hemodynamics, serum Brain natriuretic peptide (BNP), High-sensitivity troponin T (TNT-HS), Creatine kinase isozyme (CK-MB) levels were compared between the two groups. Adverse reactions were recorded. Results: After 1 week of treatment, TNT-HS, CK-MB, BNP, pulmonary wedge pressure (PCWP), left ventricular end diastolic diameter (LVEDd) and left ventricular end systolic diameter (LVESD) were significantly decreased in the two groups, and the invasive mean arterial pressure (MABP), invasive arterial systolic pressure (SBP) and left ventricular ejection fraction (LVEF) were increased, and the difference between the above indicators in the study group before and after treatment was significantly higher than that in the control group(P<0.05). The incidence rates of adverse cardiovascular events such as malignant arrhythmia, recurrent myocardial infarction, and heart failure in the study group were significantly lower than those in the control group, and the differences were statistically significant (P<0.05). Conclusion: Combined treatment of PCI and IABP for patients with AMI can effectively improve their hemodynamics, reduce BNP, CK-MB and TNT-HS levels, and effectively promote cardiac function recovery.
庞芹, 张杨春, 李璐娜. 联合应用PCI术 IABP治疗心肌梗塞患者的疗效分析[J]. 河北医学, 2022, 28(11): 1850-1853.
PANG Qin, ZHANG Yangchun, LI Luna. Analysis of the Curative Effect of Combined PCI and IABP in the Treatment of Patients with Myocardial Infarction. HeBei Med, 2022, 28(11): 1850-1853.
[1] Waha S D,Schoene K,Fuernau G,et al.Prognostic impact of atrial fibrillation in cardiogenic shock complicating acute myocardial infarction: a substudy of the IABP-SHOCK II trial[J].Clin Res Cardiol,2018,107(3):233-240. [2] 于海涛,刘东华,李淑君,等.未行经皮冠状动脉介入术治疗的急性心肌梗死合并心源性休克患者应用主动脉内球囊反搏的临床疗效[J].上海医学,2020,43(1):52-54. [3] Wu C C,Chen S W,Chou A H,et al.Nationwide cohort study of outcomes of acute myocardial infarction in patients with liver cirrhosis a nationwide cohort study[J].Medicine,2020,99(12):19575. [4] 蒙革,吴伟,冯海合,等.主动脉内球囊反搏辅助时机对高危非体外循环冠状动脉旁路移植术患者cTnⅠ和CK-MB及病死率的影响[J].临床与病理杂志,2018,38(9):58-63. [5] 孟剑锋,彭辉,李亮,等.参松养心胶囊治疗心肌损伤疗效及对CK-MB,cTnT水平的影响[J].中华中医药学刊,2020,38(1):237-240. [6] 及孟,李光智,余洪,等.破格救心汤联合重组人脑利钠肽对急性心力衰竭患者心功能及血清BNP,CK-MB和cTnI水平的影响[J].中国中医急症,2019,28(9):26-29. [7] 王学才,吴敏,罗心平,等.PCI联合IABP治疗急性心肌梗死伴心衰/心源性休克对患者心功能,血流动力学和心衰相关实验室指标的影响及其临床转归[J].微循环学杂志,2018,28(4):26-31. [8] 张清队,刁军,李莉,等.主动脉球囊反搏泵联合心脉隆注射液治疗AMI并心源性休克的临床研究[J].中西医结合心脑血管病杂志,2019,17(7):1060-1062. [9] 于晓钧,孙欣,曾庆允,等.主动脉内球囊反搏在急性心肌梗死合并心源性休克患者急诊PCI中的应用时机和效果分析[J].广东医学,2018,39(11):1667-1670.
2022, Vol. 28 
冀公网安备13080202000677号