Abstract：Objective: To explore the relationship between the type of alveolar bone defect and the postoperative effect of guided bone regeneration (GBR). Methods: A total of 82 patients who received implants in the maxillary anterior region and underwent GBR during the same period from October 2019 to October 2021 in the Department of Stomatology of Dongguan People's Hospital were retrospectively selected as the research subjects. The bone graft resorption rate was measured by cone beam CT (CBCT) in all patients after implantation. The three-dimensional structure reconstruction of bone defect was carried out according to the patient's CBCT data, the relationship between Pearson-related bone defect morphological variables and bone graft resorption rate, and the ROC curve was used to analyze the predictive value of primary bone defect morphological variables on bone graft resorption rate. Results: Six months after GBR, the average absorption rate of 82 patients was (46.8±10.52)%. After reconstruction of the initial bone defect by CBCT, the calculation showed that the mMD was (5.39±1.58) mm, the mCA was (5.24±1.08) mm, the mBL was (5.06±1.25) mm, the rmCA/mMD was (1.03±0.29), and the rmCA was (5.06±1.25) mm. /mBL was (1.07±0.27), and rmBL/mMD was (1.00±0.33). Pearson correlation analysis showed that mCA and mBL were negatively correlated with bone graft resorption rate (r=-0.408, -0.496, P<0.05); rmCA/mMD, rmCA/mBL were positively correlated with bone graft resorption rate (r=0.636, 0.418, P<0.05). Univariate and multivariate results showed that mBL and rmCA/mMD were the influencing factors of bone graft resorption rate (P<0.05). In addition, the ROC curve showed that the AUCs of mBL and rmCA/mMD for predicting bone graft resorption rate ≥45.1% were 0.836 and 0.812, respectively, and the 95% CIs were 0.743-0.921 and 0.722-0.902, respectively. Conclusion: The initial bone defect morphology was closely related to the effect of bone grafting after GBR, and the morphological characteristic variables of the bone defect had better value in predicting the postoperative bone graft resorption rate.
罗焕娣, 王玉玲, 莫浩勋, 缪小青. 牙槽骨缺损类型与GBR术后效果的关系及预测价值分析[J]. 河北医学, 2022, 28(9): 1541-1545.
LUO Huandi, WANG Yuling, MO Haoxun, et al. Analysis of the Relationship and Predictive Value between the Type of Alveolar Bone Defect and the Postoperative Outcome of GBR. HeBei Med, 2022, 28(9): 1541-1545.
2022, Vol. 28 
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