2型糖尿病合并大血管病变患者营养不良风险现状及影响因素研究

doi:10.3969/j.issn.1006-6233.2022.09.019

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摘要 目的: 探讨2型糖尿病合并大血管病变患者营养不良风险现状及影响因素,为制订营养不良预防和干预措施提供依据。方法: 选择2020年7月至2021年6月期间我院内分泌科收治的2型糖尿病患者554例,入院后评估是否合并大血管病变,同时采用NSR2002对所有患者的营养的风险进行评估,将合并大血管病变的患者中NSR≥3的患者纳入风险组,NSR<3的患者纳入对照组。对比两组患者的相关资料,并对可能造成患者营养不良风险的相关因素进行logistic多因素分析。结果: 本次研究554例2型糖尿病患者中,共447例患者合并大血管病变,大血管病变检出率为80.7%;经NSR2002评估,所有患者中有138例患者存在营养不良风险,营养不良风险检出率为24.9%。447例合并大血管病变的糖尿病患者中有122例存在营养不良风险,纳入风险组,其他325例无营养不良风险的患者纳入对照组,两组间患者的体质指数、血尿素氮水平、白蛋白水平、前脂蛋白水平、甘油三酯水平、糖化血红蛋白水平具有显著性差异,同时风险组患者的住院时间显著长于对照组患者,差异均具有统计学意义(P<0.05);经Logistic多因素回归分析模型分析后得到体质指数低、白蛋白低、甘油三酯低、糖化血红蛋白高是影响患者发生营养不良风险的危险因素,差异具有统计学意义(P<0.05)。结论: 2型糖尿病合并大血管病变的检出率较高,同时较多患者存在营养不良风险,临床上应针对相关危险因素积极识别干预,对改善患者预后具有重要价值。

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	黄秋菊
	吴军
	林双
	赖璐华

关键词 ： 2型糖尿病, 大血管病变, 营养风险筛查, 营养不良

Abstract：Objective: To explore the current situation and influencing factors of malnutrition risk in patients with type 2 diabetes mellitus complicated with macroangiopathy, to provide a basis for formulating malnutrition prevention and intervention measures. Methods: 554 patients with type 2 diabetes admitted to the Department of Endocrinology of our hospital from July 2020 to June 2021 were selected. After admission, whether they were complicated with the macrovascular disease was evaluated. At the same time, the nutritional risk of all patients was evaluated by NSR2002. Among the patients with the macrovascular disease, patients with NSR ≥ 3 were included in the risk group and patients with NSR<3 were included in the control group. The related data of the two groups were compared, and the related factors that may cause the risk of malnutrition were analyzed by logistic multifactor analysis. Results: Among 554 patients with type 2 diabetes in this study, 447 patients were complicated with macroangiopathy, and the detection rate of macroangiopathy was 80.7%; according to the evaluation of NSR2002, 138 of all patients had malnutrition risk, and the detection rate of malnutrition risk was 24.9%. Among 447 diabetes patients with the macrovascular disease, 122 patients at risk of malnutrition were included in the risk group, while the other 325 patients without malnutrition risk were included in the control group. There were significant differences in body mass index, blood urea nitrogen level, albumin level, prealbumin level, triglyceride level, and glycosylated hemoglobin level between the two groups. At the same time, the hospitalization time of patients in the risk group was significantly longer than that of patients in the control group; the difference was statistically significant (P<0.05). After the analysis of the logistic multivariate regression analysis model, it was found that low body mass index, low albumin, low triglyceride, and high glycosylated hemoglobin were the risk factors affecting the risk of malnutrition in patients, and the difference was statistically significant (P<0.05). Conclusion: Type 2 diabetes combined with macroangiopathy has a high detection rate and more patients are at risk of malnutrition. Active clinical interventions to identify associated risk factors are valuable in improving patient prognosis.

Key words： Type 2 diabetes mellitus Macrovascular disease Nutritional risk screening Innutrition

基金资助:广西壮族自治区卫生健康委员会自筹经费科研课题,(编号:Z20190101);广西壮族自治区卫生健康委员会自筹经费科研课题,(编号:Z20190300)

通讯作者: 赖璐华

引用本文:

黄秋菊, 吴军, 林双, 赖璐华. 2型糖尿病合并大血管病变患者营养不良风险现状及影响因素研究[J]. 河北医学, 2022, 28(9): 1502-1505.
HUANG Qiuju, WU Jun, LIN Shuang, et al. Study on the Current Status of Malnutrition Risk and Factors Affecting Patients with Type 2 Diabetes Mellitus Combined with Macroangiopathy. HeBei Med, 2022, 28(9): 1502-1505.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2022.09.019 或 http://www.hbyxzzs.cn/CN/Y2022/V28/I9/1502

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