Abstract:Objective: To analyze the clinical value of urethroplasty with transverse cutting pedicled prepuce island flap (Duckett operation) for hypospadias with penile head. Methods: The clinical data of 129 cases of hypospadias with small penis head treated in our hospital from March 2018 to March 2021 were retrospectively analyzed. According to the therapeutic methods, they were divided into Duckett group (n=67) and Snodgrass group (n=62). The operation-related indexes, the incidence of postoperative complications, the treatment effect and family satisfaction rate of the two groups were compared. Results: Compared with snodgrass group, the operation time and blood loss in Duckett group were higher, and the difference was statistically significant (P<0.05). The incidence of postoperative urinary fistula in Duckett group was lower than that in Snodgrass group (P<0.05). The cure rate of Duckett group was higher than that of Snodgrass group 6 months after operation, and the difference was statistically significant (P<0.05). Six months after operation, the satisfaction rate of guardians in Duckett group was 86.57%, which was higher than that in Snodgrass group (67.74%, P<0.05). Conclusion: Although Duckett's operation in the treatment of hypospadias with small penis head is more complicated and the intraoperative trauma is slightly higher than that of Snodgrass's operation, the incidence of postoperative complications in children is lower, and the cure rate and satisfaction rate of guardians are higher.
[1] Kalfa N,Gaspari L,Ollivier M,et al.Molecular genetics of hypospadias and cryptorchidism recent developments[J].Clinical Genetics,2019,95(1):122-131. [2] 胡雯.尿道下裂患儿术后并发症发生率及影响因素分析[J].河北医学,2020,26(1):134-137. [3] Yu X,Nassar N,Mastroiacovo P,et al.Hypospadias prevalence and trends in international birth defect surveillance systems,1980-2010[J].European Urology,2019,76(4):482-490. [4] 国平英,齐进春,陈彗,等.Duckett术治疗重度尿道下裂单中心效果观察[J].河北医科大学学报,2021,42(3):290-293. [5] 刘航,石秦林,林涛.尿道下裂术后并发症及其预防措施进展[J].重庆医学,2019,48(20):3545-3548. [6] Raghavan R,Romano M E,Karagas M R,et al.Pharmacologic and environmental endocrine disruptors in the pathogenesis of hypospadias:a review[J].Current Environmental Health Reports,2018,5(4):499-511. [7] Ea V,Bergougnoux A,Philibert P,et al.How far should we explore hypospadias next-generation sequencing applied to a large cohort of hypospadiac patients[J].European Urology,2021,79(4):507-515. [8] 方一圩,宋宏程,孙宁,等.尿道板纵切卷管尿道成形术在尿道下裂中的应用及远期疗效[J].临床小儿外科杂志,2020,19(12):1082-1087. [9] Lucas J,Hightower T,Weiss D A,et al.Time to complication detection after primary pediatric hypospadias repair:a large,single center,retrospective cohort analysis[J].The Journal of Urology,2020,204(2):338-344. [10] Roen K,Hegarty P.Shaping parents,shaping penises:How medical teams frame parents' decisions in response to hypospadias[J].British Journal of Health Psychology,2018,23(4):967-981. [11] Andersson M,Sjostrom S,Wangqvist M,et al.Psychosocial and sexual outcomes in adolescents following surgery for proximal hypospadias in childhood[J].The Journal of Urology,2018,200(6):1362-1370. [12] 王学军,唐耘熳,毛宇,等.尿道下裂术后尿道狭窄的再手术方法及疗效分析[J].中国修复重建外科杂志,2019,33(2):223-226.