Abstract：Objective: To explore the prognostic value of central venous-to-arterial carbon dioxide difference [P(cv-a)CO2], lactate and procalcitonin (PCT) in septic shock patients. Methods: The data of 141 septic shock patients admitted to the hospital between October 2017 and October 2020 was collected. The patients were divided into survival group (71 cases) and death group (70 cases) according to the prognosis. Multivariate logistic regression analysis was performed to analyze the relationship of serum P(cv-a)CO2, lactate and PCT levels with death of septic shock patients. Meanwhile, ROC curve analysis of serum P(cv-a)CO2, lactate and PCT levels was conducted. Results: The levels of P(cv-a)CO2, lactate and PCT in survival group were lower than those in death group (P<0.05). Multivariate logistic regression analysis found that serum P(cv-a)CO2, lactate and PCT were risk factors for death of patients with septic shock (P<0.05). ROC curve analysis showed that the area under the curve (AUC) values of serum P(cv-a)CO2, lactate and PCT to predict the prognosis were 0.951, 0.958, and 0.971, respectively. The 95%CIs were 0.901-0.980, 0.910-0.984, and 0.928-0.992. The cutoff values were 5.974, 5.257 and 9.381. The sensitivity was 87.142%, 90.001% and 92.861%. The specificity was 88.731%, 91.552% and 91.552 %. Conclusion: High serum levels of P(cv-a)CO2, lactate and PCT are related to poor prognosis of septic shock patients. All of the three have good prognostic value in septic shock patients.
严思, 湛文世, 颜光寰, 王庭学. 中心静脉-动脉血二氧化碳分压差乳酸降钙素原在评估脓毒性休克患者预后的价值[J]. 河北医学, 2022, 28(6): 892-895.
YAN Si, ZHAN Wenshi, YAN Guanghuan, et al. Prognostic Value of Central Venous-to-Arterial Carbon Dioxide Difference, Lactate and Procalcitonin in Septic Shock Patients. HeBei Med, 2022, 28(6): 892-895.
2022, Vol. 28 
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