Abstract：Objective: To investigate the effect of cardiac troponin I (cTnI) on myocardial injury in patients with thoracic tumor. Methods: During the period of 2012-2016 in our hospital, specific cTnI and creatine kinase during radiotherapy (CK-MB) monitoring results of 43 cases of patients with chest tumor (observation group) and 28 cases of non breast cancer (control group) in different time were compared; the abnormal situation of cTnI, CK-MB of two groups were analyzed; the clinical value of cTnI for monitoring the myocardial injury in patients with thoracic tumor was studied. Results: In the observation group, in addition to cTnI CK-MB before radiotherapy, DT=50Gy had no statistical difference (P>0.05); the difference between two groups were statistically significant (P<0.05); the results of DT=50Gy, DT=60-70Gy and cTnI after radiotherapy abnormal rate between the two groups by chi square test were statistically significant (P<0.05); the results of DT=60-70Gy and radiotherapy and the abnormal rate of CK-MB by chi square test were statistically significant (P<0.05). cTnI and CK-MB of the control group in the process of radiotherapy didn't appear abnormal. In the observation group, the abnormal rate of DT=60-70Gy was higher than that of CK-MB, but the difference of cTnI was statistically significant (P<0.05). Conclusion: cTnI of radiotherapy in patients with thoracic cancer early cardiac injury monitoring effect, symptomatic treatment necessary for patients with early cardiac injury of chest tumor timely adjust the irradiation scheme, to improve the quality of life of cancer patients has important clinical significance.
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2017, Vol. 23 
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