Abstract：Objective: To explore the influencing factors of perioperative infection of upper urinary tract stones and the predictive value of C reactive protein (CRP)/serum albumin (ablumin, Alb) ratio. Methods: The clinical data of 358 patients who underwent percutaneous nephrolithotomy for stone extraction due to upper urinary tract stones admitted to our hospital from June 2018 to June 2021 were retrospectively analyzed and divided into infected group (89 cases) and uninfected group (269 cases) according to whether they had perioperative infection. The risk factors for perioperative infection were analysed using multi-factor logistic regression, comparing gender, age, Body Mass Index (BMI), site of surgery, preoperative comorbidities, history of smoking and alcohol consumption, and surgery-related indexes between the two groups. The CRP/Alb ratio was compared between the two groups, and the predictive value of the CRP/Alb ratio on the occurrence of infection was analysed using the receiver operator characteristic curve (ROC). Results: The difference between the infected group and the uninfected group in terms of smoking history, operation duration>1.5h, postoperative white blood cell count, and postoperative neutrophil ratio was statistically significant, P<0.05; The CRP/Alb ratio was significantly higher in the infected group (3.15±0.46) than in the uninfected group (1.55±0.61), P<0.05; Smoking history, postoperative white blood cell count, duration of surgery > 1.5h, and CRP/Alb ratio were all independent risk factors affecting perioperative infection of upper urinary tract stones in patients, P<0.05; ROC analysis showed that the AUC of CRP/Alb ratio for predicting perioperative infection of upper urinary tract stones was 0.979, with a sensitivity of 92.1% and specificity of 93.7%, P<0.05. Conclusion: Perioperative infection of upper urinary tract calculi is affected by various factors. The presence of smoking history, postoperative leukocyte count, duration of surgery >1.5h and high CRP/Alb ratio are all risk factors for infection and should be taken into account in clinical practice; CRP/Alb has a good predictive value for the occurrence of perioperative infection in patients with urinary tract stones, and can provide a scientific basis for clinical diagnosis and treatment.
戴朝云, 杨海东, 罗景, 段南均, 范力, 姜永明. 上尿路结石围手术期感染因素及CRP/Alb的预测价值[J]. 河北医学, 2022, 28(4): 665-669.
DAI Chaoyun, YANG Haidong, LUO Jing, et al. Perioperative Infection Factors of Upper Urinary Tract Dtones and the Predictive Value of CRP/Alb. HeBei Med, 2022, 28(4): 665-669.
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2022, Vol. 28 
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