Abstract:Objective: To analyze the value of different pastes in pulp revascularization in the treatment of patients with necrotic pulpitis of young permanent teeth. Methods: A total of 92 patients with necrotic pulpitis of young permanent teeth admitted to our hospital from January 2019 to February 2020 were selected as the research subjects. They were randomly divided into control group (46 cases, 46 affected teeth) and observation group (46 cases, 46 affected teeth) by simple random grouping. Both groups were treated with pulp revascularization, the control group was treated with triple antibiotic paste, and the observation group was treated with calcium hydroxide paste. Both groups were followed up for 12 months after completion of treatment. Clinical efficacy, positive rate of bacteria after sealing, follow-up and incidence of adverse reactions during follow-up were counted in two groups 1 month after treatment. The scores of clinical symptom before treatment and 1 month after treatment, and scores of visual analogue scale (VAS) before treatment and 3, 6 and 12 months after treatment were compared between two groups. Results: The total effective rate at 1 month after treatment of observation group was 93.48%, which was significantly higher than control group at 78.26% (P<0.05). Compared with before treatment, the scores of gingival swelling, pain and tooth loosening in the two groups decreased 1 month after treatment, and gingival swelling, pain and tooth loosening scores decreased more significantly in the observation group than in the control group (P<0.05). When comparing VAS scores between the two groups, they were higher at 3, 6 and 12 months post-treatment than pre-treatment, 6 and 12 months post-treatment than 3 months post-treatment and 12 months post-treatment than 6 months post-treatment (p<0.05). 12 months after treatment, the score of VAS of observation group was lower than that of control group (P<0.05). After sealing, the positive rate of bacteria in the observation group was lower than the control group (P<0.05). During follow-up, there was no significant difference in the incidence of crown discoloration and total adverse reactions (0.00% and 4.35%, 4.35% and 10.87%) between the the observation group and the control group (P>0.05). Conclusion: The use of calcium hydroxide paste can effectively reduce the rate of bacterial positivity and post-treatment pain in patients with necrotic pulpitis in young permanent teeth, and improve the clinical symptoms of patients with better treatment effect and safety.
刘学, 胥阳, 孙雅娜, 冯建坤, 郭文静. 不同糊剂在牙髓血运重建术治疗年轻恒牙牙髓炎坏死患者中的应用价值分析[J]. 河北医学, 2022, 28(3): 490-494.
LIU Xue, XU Yang, SUN Yana, et al. Analysis of the Value of Different Pastes in Pulp Revascularization in the Treatment of Patients with Necrotic Pulpitis in Young Permanent Teeth. HeBei Med, 2022, 28(3): 490-494.
[1] Arruda M,Neves M,Diogenes A,et al.Infection control in teeth with apical periodontitis using a triple antibiotic solution or calcium hydroxide with chlorhexidine: a randomized clinical trial[J].Endod,2018,44(10):1474~1479. [2] 张明,冯岩.牙髓血运重建术用于根尖孔宽大的年轻恒牙临床疗效分析[J].口腔医学研究,2017,33(2):175~178. [3] 张震康.现代口腔医学[M].北京:科学出版社,2003.292~294. [4] Asnaashari M,Eghbal M J,Sahba Y A,et al.Comparison of antibacterial effects of photodynamic therapy,modified triple antibiotic paste and calcium hydroxide on root canals infected with enterococcusfaecalis:an in vitro study[J].Lasers Med Sci,2019,10(1):23~29. [5] Tirukkolluru C,Thakur S.Comparative evaluation of triple antibiotic paste,propolis with moxifloxacin,and calcium hydroxide as intracanal medicaments against streptococcus spp.and enterococcus faecalis in type ii diabetes mellitus patients:a randomized clinical trial[J].Contemp Clin Dent,2019,10(2):191~196. [6] 肖青锋,雷志敏,杨磊,等.牙髓血运重建术中应用BP-RRM治疗年轻恒牙牙髓坏死的临床效果[J].广西医学,2017,39(9):1292~1294. [7] 张玉杰,张楠,张雪飞,等.牙髓血运重建术中氢氧化钙髓腔封药治疗年轻恒牙牙髓炎坏死患者的临床价值研究[J].临床误诊误治,2020,33(11):105~108. [8] 蒋俊发.牙髓血运重建术对年轻恒牙根尖周病变患者相关生长因子及牙根生长的影响[J].实用医院临床杂志,2018,15(4):254~256. [9] 胡晓燕,马丽琼,潘莉.牙髓血管再生治疗牙髓坏死伴根尖周病变的年轻恒牙的两年疗效观察[J].实用口腔医学杂志,2017,33(4):469~474.