Abstract：Objective: To investigate the infection of the nosocomial incision and its influencing factors after the repair of the lower limb wound flap. Methods: 282 patients who underwent lower extremity wound flap repair in our hospital from January 2017 to December 2020 were selected for retrospective analysis. The factors that may affect the nosocomial incision infection were collected. According to the presence or absence of nosocomial incision infection, the patients were divided into infected group and uninfected group. The medical records of the two groups were compared, and the factors with significant differences in univariate analysis were comprehensively analyzed by multivariate logistic regression analysis. Results: A total of 23 of the 282 patients undergoing skin flap repair of lower limb wounds included in this study had incision infection, and the infection rate was 8.16%. A total of 36 pathogenic bacteria were isolated and cultured in 23 patients, of which gram-positive bacteria accounted for 61.11%, gram-negative bacteria accounted for 33.33%, and fungi accounted for 5.56%.On the basis of univariate analysis and multivariate analysis, the results showed that the risk factors of nosocomial incision infection after lower limb skin flap repair were the prolongation of post injury visit time, operation time, hospital stay, glucocorticoid use and diabetes history, and the protective factors were the skin lesion area more than 10% of the wound area and the use of preventive antibiotics (P<0.05). Conclusion: The rate of nosocomial incision infection after lower limb skin flap repair is high, mainly Gram-positive infection, which is mainly affected by the time of treatment, operation time, hospital stay and other factors. In clinical practice, targeted intervention can be carried out for the above factors to reduce the incidence of nosocomial incision infection in such patients.
蒲晓姝, 蒋婷, 张兰芳, 刘鸿雁. 下肢创面皮瓣修复术后院内切口感染情况及其影响因素分析[J]. 河北医学, 2021, 27(11): 1866-1871.
PU Xiaoshu, JIANG Ting, ZHANG Lanfang, et al. Analysis of Infection of Nosocomial Incision and Its Influencing Factors after Repair of Lower Extremity Wound Skin Flap. HeBei Med, 2021, 27(11): 1866-1871.
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2021, Vol. 27 
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