Abstract：Objective: To study the effect of pressing acupuncture in the treatment of children with multiple tics of wind-phlegm obstructing collaterals. Methods: This study is a prospective randomized controlled trial. The trial period is from March 2019 to March 2020. The subjects included 120 patients with wind-phlegm-resistance-type TS who were admitted to the Pediatric Clinic of the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine. Random number table method is used in dividing the patients into control group 1, control group 2 and treatment group, 40 cases in each group. During the clinical investigation, 9 cases stopped responding, and 111 cases were actually followed up, including 37 cases in the control group 1, 36 cases in the control group 2, and 38 cases in the treatment group. The control group 1 was treated with traditional acupuncture, once a day, 5 days a week for 5 days; the control group 2 was treated with tiapride hydrochloride, with initial dose of 1/3~1 tablet/time and 1/2~2 tablet/time after 2 weeks of treatment, bid; the treatment group was treated with pressing needles, embedded for 5 days, and rested for 2 days afterwards, before the next needle embedding was performed. The three groups were treated for 8 weeks. Before treatment and 8 weeks after treatment, the three groups of TCM syndrome scores were assessed according to the "Standards for the Diagnosis and Efficacy of TCM Diseases", the Yale Comprehensive Tic Severity Scale (YGTSS) was used to assess the degree of tics in the three groups, and the three groups of serum dopamine (DA) and Norepinephrine (NE), and the efficacy of the three groups after 8 weeks of treatment was determined based on the changes in the YGTSS score. Measurement data such as TCM syndrome score, YGTSS score and serum DA and NE levels were compared by analyzing variance among multiple groups. Further pairwise comparisons between groups were performed by SNK-q test. Paired t-test was used before and after treatment within the group; Chi-square test was used for curative effect. Results: After 8 weeks of treatment, the TCM syndrome scores, YGTSS scores, and serum DA and NE levels in the three groups were all reduced compared with those before treatment (P<0.05), and the above indicators in the treatment group and the control group 1 were significantly lower than those in the control group 2 (P<0.05), there is also a significant difference between the treatment group and the control group 1 (P<0.05); the total effective rate of the treatment group is significantly higher than that of the control group 1 and 2 (P<0.05). Conclusion: The therapeutic effect of pressing needle for wind-phlegm blocking-collateral TS is ideal, which can effectively adjust the levels of serum DA and NE, significantly reduce the score of TCM syndrome, and significantly improve tic symptoms.
冯秋菊, 陈晨, 杜娟, 王有鹏. 揿针在风痰阻络型儿童多发性抽动症患者治疗中的应用效果研究[J]. 河北医学, 2021, 27(10): 1739-1743.
FENG Qiuju, CHEN Chen, DU Juan, et al. Application Effect of Pressing Needle in the Treatment of Tourette Syndrome in Children with Wind Phlegm Obstructing Collaterals. HeBei Med, 2021, 27(10): 1739-1743.
2021, Vol. 27 
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