Abstract：Objective: To observe the application effect of composite transplantation of allograft dermal matrix (ADM) and autologous split-thickness skin in treating burn scars. Methods: Using random number table method, 42 patients with scar contracture after burn were divided into 2 groups. The observation group was treated with composite transplantation of ADM and autologous split-thickness skin, while the control group was treated with autologous split-thickness skin alone. The patients were followed up for 2 years to observe the survival rate of skin graft, recovery of transplanted skin, scar degree, postoperative range of motion and adverse reactions. Patient satisfaction was investigated. Results: The skin grafts in both groups survived, with a survival rate of 100%. There were no significant differences in skin color score (t=1.522, P=0.133) and sensory score (t=1.566, P=0.122) between the two groups (P>0.05). The scores of skin graft texture (t=10.916, P<0.05), flatness (t=7.817, P<0.05) and contracture (t=5.519, P<0.05) of the observation group were significantly lower than those of the control group (P<0.05). The scar degree of skin graft in the observation group was significantly milder than that in the control group (z=4.926, P=0.026). The range of motion of both groups recovered well (P>0.05). There were no significant differences in the incidences of pain (χ2=0.096, P=0.757) and itching (χ2=0.697, P=0.404) between the two groups. The satisfaction rate in the observation group was 90.91%, significantly higher than 50.00% in the control group (z=8.922, P=0.003). Conclusion: Applying composite transplantation of ADM and autologous split-thickness skin to treat burn scars can achieve better recovery effect of appearance, milder scar degree and good recovery of joint function, thereby improving patient satisfaction.
2021, Vol. 27 
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