Abstract：Objective: To explore the effects of anti-infective drugs on the treatment of mild bacterial infections in pregnant women and the health of mothers and babies. Methods: From January 2019 to January 2020, 120 patients with mild bacterial infections during pregnancy who were admitted to Chengde Central Hospital were selected. All patients underwent normal obstetric examinations. According to simple random grouping, they were divided into observation group and control group, each with 60 cases. The observation group was treated with antibiotics after a mild bacterial infection during pregnancy, while the control group was not treated with antibiotics after a mild bacterial infection. The infection sites of the two groups of patients were compared, and the antibiotic usage in the observation group was counted. Compare the use of antibiotics on the impact of the two groups of pregnant women during the entire pregnancy, such as poor pregnancy (premature delivery, premature rupture of membranes, abortion, etc.), and at the same time the last B-ultrasound results (fetal double parietal diameter, femoral length , Birth weight, birth gestational age) for comparative analysis. Results: The distribution of the two groups of patients in the digestive system, respiratory system, urinary system, and reproductive system was relatively consistent, and there was no statistical difference (P>0.05); the types of antibiotics used in the observation group were as follows: 30 third-generation cephalosporins ( 50.00%), 18 cases of penicillins (30.00%), 6 cases of macrolides (10.00%), 4 cases of lincomycins (6.67%), and 2 cases of tetracycline antibiotics (3.33%). The most used is the third-generation cephalosporin. The incidence of adverse pregnancy (premature delivery, premature rupture of membranes, miscarriage, etc.) in the observation group was 8.33% (5/60), which was significantly lower than that of the control group (35.00%, 21/60), and the difference was statistically significant (χ2=12.570) , P<0.01); Compared with the control group, the observation group’s last B-ultrasound examination before labor, the developmental indicators such as the length of the double parietal diameter and the length of the femur, and the birth weight of the fetus were significantly increased, with statistical differences (P<0.05).Conclusion: Mild bacterial infections occur during pregnancy. Reasonable use of antibiotics can reduce the incidence of adverse pregnancy and is of great significance for improving the outcome of childbirth.
姚淑慧, 孟爱霞. 抗生素的使用对妊娠合并轻症细菌感染性疾病孕妇妊娠结局的影响研究[J]. 河北医学, 2021, 27(7): 1197-1199.
YAO Shuhui, et al. Study on the Effect of Antibiotics on Pregnancy Outcome of Pregnant Women with Mild Bacterial Infections. HeBei Med, 2021, 27(7): 1197-1199.
2021, Vol. 27 
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