Abstract：Objective: To study the effect of Icotinib tablets combined with stereotactic body radiotherapy (SBRT) on patients with non-small cell lung cancer (NSCLC) serum tumor markers, and to provide a reference for better treatment of the disease. Method: A total of 65 NSCLC patients diagnosed and treated in our hospital from August 2017 to April 2020 were prospectively studied. They were randomly divided into a control group of 33 cases with SBRT as treatment, and an observation group of 32 cases with Icotinib tablets for combination therapy on the basis of SBRT treatment. Both groups were treated for one month. The serum tumor marker levels of patients were compared before treatment and within 4 to 12 hours after treatment. Results: After treatment, the levels of serum tumor markers CEA, CA125, CYFRA21-1 [(3.12 ± 1.45), (30.12 ± 3.25), (5.27 ± 1.89), μg / L] were significantly lower than the control group [(5.34 ± 1.83 ), (45.34 ± 4.87), (8.74 ± 2.15), μg / L]; the difference is statistically significant (P<0.05). Conclusion: The combination of Icotinib and SBRT can reduce the level of serum tumor markers to a greater extent and has a better effect.
赵洁, 宁鹏, 刘海明. 埃克替尼片联合SBRT治疗对NSCLC血清肿瘤标志物的影响[J]. 河北医学, 2021, 27(4): 697-700.
ZHAO Jie, NING Peng, LIU Haiming. Effect of Icotinib Combined with SBRT on Serum Tumor Markers in Patients with NSCLC. HeBei Med, 2021, 27(4): 697-700.
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2021, Vol. 27 
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