Abstract：Objective: To explore the distribution of pathogenic bacteria associated with intervertebral space infection after lumbar disc herniation (LDH) and analyze its influencing factors.Methods: From March 2013 to March 2020, 895 patients with LDH who were admitted to our hospital and underwent surgical treatment were screened out. Based on whether they had postoperative complications of intervertebral space infection, they were divided into observation group (complicated infection, 38 cases) and control group (857 cases without concurrent infection). Statistics of postoperative LDH complicated intervertebral space infection and the distribution of pathogenic bacteria were recorded, the clinical data of the two groups were reviewed, and the influencing factors were analyzed. Results: Among the 895 cases of LDH patients, 38 cases (4.25%) had postoperative complications of intervertebral space infection, 8 cases failed to detect pathogenic bacteria, and 33 pathogenic bacteria were detected in the other 30 cases. The detection rate of Staphylococcus aureus was the highest, accounting for 30.30%, followed by Staphylococcus epidermidis (21.21%) and Escherichia coli (15.15%). The univariate results showed that age, history of diabetes, BMI, malnutrition, operation time, and postoperative infections of other systems were the influencing factors of intervertebral space infection after LDH. Multivariate logistic regression analysis showed that age ≥55 years old, history of diabetes, BMI≥27kg/m2, malnutrition, operation time ≥3h, postoperative infection of other systems were independent risk factors for postoperative LDH complicated with intervertebral space infection. Conclusion: In clinical practice, LDH is not easy to be complicated with intervertebral space infection, and the incidence is at a low level. However, it is still necessary to pay attention to the independent risk factors of complicated intervertebral space infection during postoperative rehabilitation, and it can be reasonably applied based on the distribution of pathogens. Antibiotics are used to prevent and standardize operations to reduce or avoid postoperative intervertebral space infection.
赵兵, 黄海锋, 尹振宇, 羊刚毅, 宋晋刚. 腰椎间盘突出症术后椎间隙感染病原菌分布及影响因素分析[J]. 河北医学, 2021, 27(4): 620-625.
ZHAO Bing, HUANG Haifeng, YIN Zhenyu, et al. An Analysis of Pathogenic Bacteria Distribution and Influencing Factors of Intervertebral Space Infection After Lumbar Disc Herniation. HeBei Med, 2021, 27(4): 620-625.
2021, Vol. 27 
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