Abstract：Objective: To analyze and explore the clinical value of combined detection of antinuclear antibodies and antinuclear antibodies in the diagnosis of autoimmune diseases. Method: 1103 blood samples were submitted to our hospital, antinuclear antibody detection and antinuclear antibody spectrum detection were simultaneously tested. Antinuclear antibodies were detected by indirect immunofluorescence, and antinuclear antibodies were detected by Western blot. The data of patients with positive results were collected and analyzed statistically. Results: The positive results of antinuclear antibody test accounted for 6.32% of all patients, and the diagnosis accuracy was 78.21%; Detection of antinuclear antibody spectrum of blood test positive patients accounted for 4.78% of all patients, the diagnosis results showed that antinuclear antibody spectrum diagnosis rate was 91.32%, and the two methods were both positive patients for inspection, found that the highest accuracy is 94.67%. Conclusion: Simultaneous detection of antinuclear antibodies and antinuclear antibody spectrum can effectively improve the accuracy of the detection results, and is worthy of promotion.
陈向华, 王建吉, 耿学丽, 丁萌, 张秀琴. 抗核抗体和抗核抗体谱联合检测诊断自身免疫性疾病的临床价值[J]. 河北医学, 2017, 23(8): 1278-1280.
CHEN Xianghua, et al. Clinical Value of the Diagnosis of Autoimmune Diseases by Antinuclear Antibody Combined and Antinuclear Antibody. 河北医学, 2017, 23(8): 1278-1280.
2017, Vol. 23 
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