Abstract：Objective: To observe the clinical significance and the changes on the neutrophil-to-lymphocyte, the eosinophil-to-lymphocyte, the platelet-to-lymphocyte with Neonatal septicemia. Methods: From April 2017 to May 2020, 58 newborns with early-onset sepsis in our hospital were selected as sepsis group, and 40 non infected newborns in the same period were selected as control group. The levels of NLR, ELR and PLR were compared between the two groups. The changes and clinical significance of NLR, ELR and PLR in early-onset neonatal sepsis were evaluated. Results: The levels of NLR and ELR in sepsis group were significantly higher than those in control group (P<0.05). ROC curve analysis showed that area under the curve NLR > ELR > PLR, NLR cutoff value was 1.987, sensitivity was 78.87%, specificity was 88.11%, area under the curve was 0.752, ELR cutoff value was 0.117, sensitivity was 70.81%, specificity was 77.25%, area under the curve was 0.689. Conclusion: The diagnostic efficiency of NLR is higher than that of ELR, which can assist in the diagnosis of early-onset neonatal sepsis, and has a certain reference value for the diagnosis and evaluation of children's diseases.
2021, Vol. 27 
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