Predictive Value of Fractional Flow Reserve Combined with Serum ESM-1 Level for Cardiovascular Events and In-Stent Restenosisin Patients with AMI After PCI
HUANG Qi, CUI Yan, FU Yingjie
Shanghai Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200086, China
Abstract：Objective: To explore predictive value of fractional flow reserve (FFR) combined with serum endothelial cell specific molecule 1 (ESM-1) level for cardiovascular events (CE) and in-stent restenosis (ISR) in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). Methods: The influencing factors of CE and ISR in the 182 AMI patients after PCI, and the predictive value of FFR combined with ESM-1 for CE and ISR were retrospectively analyzed. Results: ESM-1 in CE group and ISR group was higher than that in non-cardiovascular event (NCE) group and non-ISR (NISR) group, while FFR was lower than that in NCE group and NISR group, respectively (P<0.05). AUC values of FFR combined with ESM-1 for predicting CE and ISR were 0.874 and 0.884, which were higher than those of single index (P<0.05). ESM-1 was an independent risk factor of CE, and FFR was an independent protective factor of ISR within 1 year after PCI in AMI patients (P<0.05). Conclusion: ESM-1 was an independent risk factor of CE and ISR within 1 year after PCI in AMI patients, while FFR was an independent protective factor. The predictive value of their combination detection for CE and ISR is relatively higher.
黄麒, 崔燕, 傅英杰. 血流储备分数联合血清ESM-1水平对急性心肌梗死患者PCI术后心血管事件和支架内再狭窄的预测价值[J]. 河北医学, 2021, 27(1): 61-65.
HUANG Qi, CUI Yan, FU Yingjie. Predictive Value of Fractional Flow Reserve Combined with Serum ESM-1 Level for Cardiovascular Events and In-Stent Restenosisin Patients with AMI After PCI. HeBei Med, 2021, 27(1): 61-65.
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2021, Vol. 27 
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