Abstract：Objective: To investigate the effects of propofol of different target concentrations combined with remifentanil, and sevoflurane combined with remifentanil inhalation anesthesia in patients undergoing laparoscopic cholecystectomy. Methods: A total of 100 patients with laparoscopic resection admitted to our hospital from March 2019 to September 2019 were selected and divided into observation group and control group with random number table, with 50 cases in each group. The control group received propofol combined with remifentanil anesthesia, and the observation group received sevoflurane combined with remifentanil inhalation anesthesia. The effects of anesthesia and hemodynamics parameters and adverse reactions were compared between the two groups. Results: In the observation group, MAP and HR levels in T1 and T2 stagesn were significantly higher than those of the control group (all P<0.05), and MAP and HR levels in T4 and T5 stages were significantly lower than those in the control group (all P<0.05). While at stages T2 and T5, SpO2 of the observation group was significantly lower than that of the control group (all P<0.05). The recovery time of spontaneous breathing, eye opening time, speech response time and directional power recovery time of patients in the observation group were significantly shorter than those in the control group (all P<0.05). Conclusion: Clinical use of sevoflurane remifentanil intravenous anesthesia in LC surgery can significantly maintain hemodynamic stability, shorten the time of spontaneous breathing recovery, eye-opening, speech response and orientation recovery. It has good clinical application value.
2021, Vol. 27 
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