Abstract：Objective: To explore the effect of serum alcohol concentration (BAC) on inflammation and CT imaging characteristics in patients with craniocerebral trauma. Methods: 106 patients with craniocerebral injury admitted in our hospital from October 2018 to October 2019 were selected as the research object. Gas chromatography was used to measure the BAC of the patients. According to the alcohol concentration, the patients were divided into alcohol-positive group (BAC>0.05%) and alcohol-negative group (BAC <0.05%), with 42 and 64 cases respectively. All patients underwent CT scan to compare the serum inflammatory response index level and CT image characteristics of the two groups of patients. Results: The systolic blood pressure, heart rate and body temperature of the alcohol-positive group were significantly lower than those of the alcohol-negative group, while the respiratory frequency BAC level was significantly higher than that of the alcohol-negative group (P<0.05). The results of rank sum test showed that there was no statistically significant difference in Rotterdam CT scores between the two groups (P>0.05), but the proportion of patients with Rotterdam CT scores of 4, 5 and 6 in the alcohol-positive group was significantly higher than that in the alcohol-negative group. The levels of serum IL-6, TNF-α, CRP and WBC in the alcohol positive group were significantly lower than those in the alcohol negative group (P<0.05). The BAC of patients with craniocerebral injury was positively correlated with serum IL-6, TNF-α, CRP and WBC counts, and the Pearson correlation coefficient r was 0.931, 0.467, 0.863, 0.935 respectively (P<0.05), which was not related to Rotterdam CT score (P>0.05). Conclusion: BAC can participate in the process of inflammation in patients with cranial head injury and can reduce the degree of inflammation in patients, but it has no obvious influence on Rotterdam CT score.
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2020, Vol. 26 
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