Abstract：Objective: To investigate the value of high-frequency ultrasound (HFUS) of wrist and finger joint in the diagnosis and differential diagnosis of rheumatoid arthritis (RA) and hand osteoarthritis(OA).And to analyze the value of semi-quantitative ultrasound score in the assessment of disease activity of RA.Methods: 54 patients with RA were enrolled,and 30 patients with hand OA were selected as control group.Wrist joints,metacarpophalangeal and proximal interphalangeal joints were examined by high-frequency ultrasound.The thickness of synovial membranes,synovial blood flow,bone erosion and tenosynovitis were measured.Semi-quantitative ultrasound scores of the above four indexes were calculated.And laboratory characteristics were carefully recorded,including ESR,CRP,RF,anti-CCP and DAS28 scores in the RA group.The correlation between ultrasound scores and clinical indicators were analyzed.Results: RA group was significantly more than OA group with synovial hyperplasia,synovial blood flow,bone erosion and tenosynovitis (P<0.01).There were significant positive correlation between semi-quantitative ultrasound score and DAS28 score (r=0.550,P<0.05).Conclusion: High-frequency ultrasound was valuable in the diagnosis and differential diagnosis of RA and hand OA.Semi-quantitative ultrasound score can reflect the disease activity in RA.
张颖, 孟景红, 谢建丽, 李静, 陈海英, 王俊祥. 腕指关节高频超声在类风湿关节炎诊断及鉴别诊断中的应用价值[J]. 河北医学, 2020, 26(11): 1864-1868.
ZHANG Ying, MENG Jinghong, XIE Jianli, et al. Value of High-Frequency Ultrasound of Wrist and Finger Joint in the Diagnosis and Differential Diagnosis of Rheumatoid Arthritis. HeBei Med, 2020, 26(11): 1864-1868.
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2020, Vol. 26 
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