Abstract：Objective: To investigate the value of plasma N-terminal B-type natriuretic peptide (NT proBNP), Troponin (cTnI), D-Dimer (D-D) levels in the risk of acute pulmonary embolism (APE). Methods: The clinical data of 120 patients with high-risk APE admitted to the hospital from January 2017 to January 2019 were analyzed retrospectively. The proportion of APE patients was statistically analyzed. The levels of NT proBNP, cTnI and D-D were compared between the occurrence group and the non-occurrence group. The plasma NT-proBNP, cTnI, and D-D levels were analyzed to evaluate whether APE occurred in high-risk APE. Results: The patients who got APT accounted for 22.88%, and the levels of NT proBNP, cTnI and D-D in the occurrence group were higher than that in the non-occurrence group (P<0.05). Plasma NT-proBNP, cTnI, D-D levels had the best cutoff points to assess whether APE occurs, which were 1987.38pg/mL, 75.41μg/mL and 5.86mg/L, and the specificity and AUC of the combination of NT proBNP, cTnI and D-D were the highest. There were significant differences between the AUC of NT proBNP, cTnI and D-D level combination assessment and those of single assessment (P<0.05). Conclusion: The levels of NT proBNP, cTnI and D-D in the plasma of APE patients are all increased, and the combination of the levels of NT proBNP, cTnI and D-D is ideal to the evaluation of the occurrence of APE.
王青松, 王珠秀. 血浆NT-proBNP cTnI D-D水平对急性肺栓塞发病风险的评估价值[J]. 河北医学, 2020, 26(10): 1720-1723.
WANG Qingsong, WANG Zhuxiu. A Value Assessment of NT ProBNP, CTnI and D-D Levels in the Risk of Acute Pulmonary Embolism. HeBei Med, 2020, 26(10): 1720-1723.
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2020, Vol. 26 
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