Abstract:Objective: To study the effect of Coflex implantation and total lamina decompression bone grafting fusion and internal fixation in the treatment of senile degenerative lumbar spinal stenosis. Methods: A retrospective analysis was conducted among 62 cases of hospitalized elderly patients with degenerative lumbar spinal stenosis disease from January 2018 to June 2019. Patients were divided into two groups according to the different operation methods, namely the control group and the research group, 31 cases in each. The former were treated with total lamina decompression bone grafting fusion and internal fixation, and the latter were treated with Coflex implantation. Pre- and post-operative data of both groups were compared, including the evaluation values with Japanese Orthopaedic Association (JOA), Visual Analogue Scale (VAS) and intraoperative blood loss, operative time, wound drainage volume, length of hospital stay and incidence rate of complication. Results: JOA score, VAS score, intraoperative blood loss, operation time, wound drainage volume, length of hospital stay and complication rate of the research group were (22.48±2.74), (2.52±0.31), (106.43±17.62) mL, (64.89±8.48) min, (80.52±16.07) mL, (5.48±0.91) d, and (3.23%) respectively. Those of the control group were (20.72±2.41) points, (3.06±0.64) points, (178.25±24.81) mL, (114.72±15.63) min, (136.41±25.26) mL, (8.75±1.52) d, and 9.68%. Compared with the control group, the research group had higher postoperative JOA score, lower VAS score, shorter operative time and hospitalization time, and less intraoperative blood loss and wound drainage (P<0.05).The incidence rate of postoperative complications of the study group was slightly lower than that of the control group, but the difference was not statistically significant (P>0.05). Conclusion: The effect of Coflex implantation in the treatment of senile patients with degenerative lumbar spinal stenosis is better than that of total lamina decompression bone grafting fusion and internal fixation, with high safety and effectiveness.