Abstract：Objective: To evaluate the patent ductus arteriosus (PDA) on left ventricular (LV) systolic myocardial function in preterm infants with vector velocity imaging (VVI).Methods: Infants whose gestational age was less than 30 weeks and who were delivered in our hospital were enrolled in the study.Babies were categorized into three groups with the degrees of ductal patency evaluated with echocardiography on the third day after birth, ① Group hsPDA (hemodynamically significant PDA): PDA diameter≥1.5 mm and left atrium to aorta (LA:Ao) ratio ≥1.5; ② Group PDA: PDA diameter <1.5mm or LA:Ao ratio <1.5; ③ Group nPDA: No PDA was detected through examination.The clinical data, conventional echocardiographic parameters and LV longitudinal global peak systolic strain (LVS) and strain rate (LVSR) were recorded and compared within three groups, and analysis was conducted with one-way ANOVA.Results: The gestational age, birth weight and left ventricular ejection fraction (LVEF) were not different within the three groups (p>0.05).The conventional parameters such as LA:Ao, LV end-diastolic diameter (LVD) and E/e were significantly higher in group hsPDA than the other two groups (p<0.01), while those were not different between Group PDA and nPDA.The LV systolic myocardial function parameters LVS and LVSR were significantly lower in group hsPDA than in the other two groups (p<0.01), but those were not significant between group PDA and group nPDA although the former had lower trend (p>0.05).Conclusion: PDA in preterm infants have LV volume overload, the LV myocardial deformation already decreased despite preserved LVEF.
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2020, Vol. 26 
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