Abstract：Objective: To analyze the effect of laser lithotripsy under the guidance of B-ultrasound on children's upper urinary tract calculi.Methods: The clinical data of 210 cases of upper urinary tract calculi admitted to our hospital from November 2013 to November 2018 were retrospectively analyzed.They were divided into observation group (n=105) and control group (n=105).The control group was treated with ureterolithotomy and the observation group was treated with holmium laser lithotripsy under theguidance of B-ultrasound.The perioperative indexes, stone-free rate, white blood cell count (WBC), hemoglobin (Hb), serum inflammatory cytokines [interleukin-6(IL-6),interleukin-2(IL-2),tumornecrosis factor-α(TNF-α)], incidence of complications and recurrence rate were compared between the two groups.Results: The operation time in observation group was longer than that in control group, postoperative hospital stay was shorter than that in control group, intraoperative blood loss was less than that in control group (P<0.05), and stone free rate was lower than that in control group (P<0.05).After 24h of surgery, WBC level in observation group was lower than that in control group, while Hb level was higher than that in control group (P<0.05).The serum levels of IL-6 and TNF-α in the observation group were lower than those in the control group, and IL-2 was higher than that in the control group(P<0.05).The incidence of complications in observation group was lower than that in the control group (P<0.05).There was no significant difference in recurrence rate between the two groups (P>0.05).Conclusion: The operation time of holmium laser lithotripsy guided by B ultrasound is shorter, the amount of bleeding is less, the length of hospital stay can be shortened, and the safety is higher.The stone free rate of ureterolithotomy is higher, but the complications are more, so the appropriate operation scheme should be selected according to the actual situation of children.
2020, Vol. 26 
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