Abstract：Objective: To investigate the effects of different plate internal fixation techniques on serum substance P (SP), neuropeptide (NPY) levels and knee joint function in patients with tibial plateau fractures.Methods: From January 2017 to September 2018, 74 patients with tibial plateau fractures in our hospital were prospectively studied and randomly categorized into two groups with random number table method, 37 cases in each.Group A underwent minimally invasive internal fixation system (LISS) plate technology, and group B underwent anatomical plate internal fixation.The operative indexes, complication rate, perioperative pain stress (serum SP, NPY), varus angle, caster angle, knee joint range of motion and distinguished achiever ratio of knee joint function recovery at three months, six months and twelve months after the operation were compared.Results: The operation time, intraoperative blood loss, and postoperative drainage volume of group A were lower than those of group B, and the length of the incision was shorter than that of group B (P<0.05); serum SP and NPY levels in group A were lower than those in group B at the first, third, and seventh days after surgery (P<0.05); there was no significant difference between the two groups after three, six, and twelve months of varus angle, caster angle, knee joint range of motion (P>0.05); the excellent recovery rate of knee function in group A (81.08%) was not significantly different from that in group B (78.38%) (P>0.05); there was no significant difference in the incidence of complications between group A and group B (P>0.05).Conclusion: The anatomical plate internal fixation technology and LISS plate internal fixation technology have high safety and good knee joint function recovery.However, compared with the anatomical plate internal fixation technique, the LISS plate internal fixation technique has a shorter incision, which can obviously reduce the amount of intraoperative bleeding in patients with tibial plateau fractures, reduce the postoperative pain stress response, and accelerate the postoperative rehabilitation process, with high clinical promotion value.
张鹏贵, 刘烈东, 董建彬, 苏海卿. 不同钢板内固定技术对胫骨平台骨折患者血清SP NPY水平及膝关节功能的影响[J]. 河北医学, 2020, 26(9): 1473-1478.
ZHANG Penggui, LIU Liedong, DONG Jianbin, et al. Effects of Different Plate Internal Fixation Techniques on Serum SP, NPY Levels and Knee Joint Function in Patients with Tibial Plateau Fractures. HeBei Med, 2020, 26(9): 1473-1478.
[1] Zhu Y,Liu S,Zhang X,et al.Incidence and risks for surgical site infection after adult tibial plateau fractures treated by ORIF: a prospective multicentre study: SSI after tibial plateau fracture[J].Int Wound,2017,14(6):982~988. [2] Jiang L,Zheng Q,Pan Z .Comparison of extended anterolateral approach in treatment of simple/complex tibial plateau fracture with posterolateral tibial plateau fracture[J].Orthop Surg Res,2018,13(1):303. [3] 曹向宇,石利涛,张立超.微创结合开放手术对胫骨平台骨折合并半月板的临床疗效观察[J].河北医学,2018,24(12):1981~1987. [4] Kfuri M,Schatzker J.Revisiting the Schatzker classification of tibial plateau fractures[J].Injury,2018,49(12):2252~2263. [5] 范海峰.胫骨平台复杂性骨折给予LISS及单切口双钢板支撑内固定术的临床研究[J].数理医药学杂志,2018,31(1):23~24. [6] 邹创锋,蔡莉.微创内固定系统和解剖钢板治疗胫骨平台骨折的疗效对比[J].中国伤残医学,2018,26(16):9~11. [7] Sun JX,Bai KY,Liu YF,et al.Effect of local wound infiltration with ropivacaine on postoperative pain relief and stress response reduction after open hepatectomy[J].World Gastroenterol,2017,23(36):6733~6740. [8] 石武谛,柯雯昙.关节镜下经皮微创钢板内固定术与切开复位内固定术对胫骨平台骨折患者膝关节活动度、疼痛应激和炎性因子的影响比较[J].创伤外科杂志,2019,21(3):201~205. [9] 李云泽.脊髓内NF-kappa B p65信号通路在膝关节骨性关节炎所致痛觉敏感中的作用[D].山东大学,2017. [10] 易龙.微创LISS与T型钢板固定术治疗胫骨平台骨折的疗效对比观察[J].吉林医学,2018,39(6):1138~1141.
2020, Vol. 26 
冀公网安备13080202000677号