Abstract：Objective: To understand pathogens distribution and drug resistance of HAP after craniocerebral operation, and to provide evidence for clinical anti-infection empirical treatment. Methods: A retrospective analysis was conducted on the bacteria and their drug-resistance of urinarytract infections isolated from the sputum specimens of 60 pneumonia patients from January 2018to August 2018 after their intracranial surgery. Results: 185 strains of pathogens were found, including 165 strains of gram negative bacteria, accounting for 89.19%, gram positive bacteria, 18 strains, accounting for 9.73% and 2 strains of fungi, accounting for 1.08%.The detection rate of the top five pathogens were 57 strains of Pseudomonas aeruginosa, accounting for 30.81%, 32 strains of Klebsiella pneumonia, accounting for 17.3%, Bauman 27 Acinetobacter strains, accounting for 14.59%, 25 strains of Escherichia coli, accounting for 13.51%, and 12 strains of Serratia liquefaciens, accounting for 6.49%. Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Serratia liquefaction have better sensitivity to imipenem, meropenem, cefoperazone sulbactam, piperacillin tazobactam, amikacin, ciprofloxacin and cefepime. Acinetobacter baumannii only has good sensitivity to cefoperazone sulbactam, and has resistance to other drugs. Vancomycin-resistant strains of Staphylococcus aureus was not found, and it has a good sensitivity to doxycycline and minocycline. Conclusion: After craniocerebral operation, most common infection microorganism of HAP was Gram-negative bacteria, and parts showed multidrug resistance.
穆怀博, 宋超. 颅脑手术后医院获得性肺炎病原菌分布及耐药性分析[J]. 河北医学, 2020, 26(8): 1352-1356.
MU Huaibo, SONG Chao. Distribution and Drug Resistance of Nosocomial Pneumonia Pathogens After Craniocerebral Surgery. HeBei Med, 2020, 26(8): 1352-1356.
2020, Vol. 26 
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