Abstract：Objective: To analyze the diagnostic results of CT-guided needle biopsy for solitary pulmonary nodules of different sizes. Methods: A total of 108 patients with solitary pulmonary nodules admitted to our hospital from December 2013 to December 2018 were selected and grouped according to the size of lesions. The patients with size>2 cm were set as group A (n=58), and those with size ≤2 cm were set as group B (n=50). CT-guided needle biopsy was performed in the two groups. The needle biopsy results, surgical pathological results and complications were compared between the two groups. Results: The success rate of one-time puncture in group A was significantly higher than that in group B (93.10% vs 80.00%) (χ2=4.086, P<0.05). The accuracy rate of diagnosis in group A was significantly higher than that in group B (89.66% vs 74.00%), the puncture frequency in group A was significantly lower than that in group B [(1.07±0.25) vs (1.20±0.38)]. (χ2=4.539, t=2.126, P<0.05). The incidence rate of complications in group A was significantly lower than that in group B (13.79% vs 30.00%) (χ2=4.208, P<0.05). Conclusion: CT-guided needle biopsy is a simple and reliable technique, and it can accurately identify the benign and malignant solitary pulmonary nodules. However, it has low success rate of puncture, low accuracy rate of pathological diagnosis and many complications on solitary pulmonary nodules with lesion size≤ 2cm, and there is still a certain risk.
2020, Vol. 26 
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