Abstract：Objective: To analyze the application value of diffusion-weighted magnetic resonance imaging (DWI-MRI) in the evaluation of chemoradiotherapy efficacy in cervical cancer. Methods: The clinical data of 164 patients with cervical cancer who underwent chemoradiotherapy were retrospectively analyzed. The changes of apparent diffusion coefficient (ADC) were recorded in 164 patients before chemoradiotherapy and at 2, 4 and 8 w of chemoradiotherapy, and the patients were divided into complete remission (CR) group, partial remission (PR) group, stability of disease (SD) group and progression of disease (PD) group according to the efficacy at the end of chemoradiotherapy. The ADC values of each group before and after chemoradiotherapy were compared. Results: The ADC values of 164 patients at each time point after chemoradiotherapy were higher than those before chemoradiotherapy (P<0.05), and the value showed 8 w of chemoradiotherapy > 4 w of chemoradiotherapy > 2 w of chemoradiotherapy (P<0.05). Among 164 patients, 44 cases with CR were enrolled in CR group, and 96 cases with PR were included in PR group, and 24 cases with SD were included in SD group and 0 case in PD group. Before chemoradiotherapy, there was no significant difference in ADC value among the three groups (P>0.05). After chemoradiotherapy, the ADC values in the three groups were higher than those before chemoradiotherapy (P<0.05), and the values showed CR group > PR group > SD group (P<0.05). Conclusion: DWI-MRI has a high application value in the evaluation of chemoradiotherapy efficacy in cervical cancer, and it can as early as possible diagnose the efficacy of chemoradiotherapy, and it is favorable for clinical treatment.
邱文伟, 彭雨彬, 郝强. DWI-MRI在宫颈癌放化疗疗效评价中的应用[J]. 河北医学, 2020, 26(7): 1175-1177.
QIU Wenwei, PENG Yubin, et al. Research on the Application of DWI-MRI in the Evaluation of Chemoradiotherapy Efficacy in Cervical Cancer. HeBei Med, 2020, 26(7): 1175-1177.
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2020, Vol. 26 
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