Abstract：Objective: To observe the effect of different surgical methods on the quality of sexual life and pregnancy outcome of infertile patients with endometrial polyp (EP). Methods:A retrospective analysis was made, involving 106 EP infertility patients having hospitalized from May 2017 to August 2018 who were grouped according to the surgical protocol, 53 cases in each of the clamping group and the resection group. The clamping group demanded mechanical removal with hysteroscopic polyp clamp and the resection group demanded hysteroscopic endometrial polypectomy through electrosurgical. Endometrial thickness,menstrual hemorrhage map (PBAC) score, intrauterine cytokines [interleukin-1β(IL-1β), interferon gamma (IFN-γ), insulin-like growth factor-1(IGF-1)] level, quality of sexual life, recurrence rate at one year follow-up, and pregnancy outcome were compared between the two groups before and after surgery. Results:Three months after operation, the resection group was reported with the endometrial thickness smaller and the PBAC score lower than clamping group(P<0.05) ; Cytokines in the uterine fluid: Three months after operation, the resection group was reported with levels of IL-1β, IFN-γ, and IGF-1 in the uterine fluid lower than clamping group(P<0.05); Quality of sexual life: six months after operation, the resection group reported higher sexual satisfaction and weekly frequency of sexual life, shorter sexual arousal time and longer orgasm duration than clamping group(P<0.05);Recurrence rate: Nine and twelve months after operation, the resection group reported lower recurrence rate than the clamping group (P<0.05); Outcome of pregnancy: After 12 months of follow-up, the intrauterine pregnancy rate in the resection group (74.51%) was higher than that in the clamping group (52.00%) (P<0.05). Conclusion:Compared with hysteroscopic polypectomy,hysteroscopic endometrial polypectomy can significantly improve the endometrial thickness of EP infertile patients, reduce menstrual volume, improve the quality of sexual life and intrauterine pregnancy rate, and has higher safety.
刘晶晶, 张晓光, 袁凤云. 不同手术方式对子宫内膜息肉不孕患者性生活质量及妊娠结局的影响[J]. 河北医学, 2020, 26(5): 863-868.
LIU Jingjing, ZHANG Xiaoguang, YUAN Fengyun. The Effect of Surgical Options on the Quality of Sexual Life and Pregnancy of Infertile Patients with Endometrial Polyp. HeBei Med, 2020, 26(5): 863-868.
2020, Vol. 26 
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