Abstract：Objective: To analyze the effect of single and continuous injection of dexmedetomidine on hemodynamics in patients undergoing laparoscopic myomectomy. Methods: From August 2017 to August 2019, 100 patients with laparoscopic myomectomy were randomly divided into study group and control group, 50 cases in each. Patients in the control group were given continuous injection of dexmedetomidine, while those in the study group were given single injection of dexmedetomidine. The operation time, extubation time, recovery time, observers assessment of alertness/sedation scale (OAA/S) score, perioperative heart rate, systolic blood pressure, diastolic blood pressure and adverse reactions were compared between the two groups. Results: There was no significant difference in operation time between the two groups (P>0.05). The recovery time, extubation time and recovery time of anesthesia in the study group were significantly shorter than those in the control group (P<0.001). Compared with the control group, the proportion of4 and 5 points on OAA/S scores in the study group was significantly increased, and the proportion of one point on OAA/S score was significantly decreased (P<0.05). There was no statistical significance in the difference of perioperative blood pressure between the two groups (P>0.05). The heart rate of the two groups at the time of extubation and 5 minutes after extubation was significantly faster than that before operation (P<0.05). The total incidence of adverse reactions in the study group was 12.00%, which was significantly lower than that in the control group (32.00%) (P<0.05). Conclusion: Single injection of dexmedetomidine has a good anesthetic effect on patients undergoing laparoscopic myomectomy, which is conducive to maintaining hemodynamic stability.
马甫营, 王胜斌. 单次注射与持续注射右美托咪定对腹腔镜下子宫肌瘤剔除术患者血流动力学的影响[J]. 河北医学, 2020, 26(5): 751-754.
MA Fuying, WANG Shengbin. Effects of Single and Continuous Injection of Dexmedetomidine on Hemodynamics in Patients Undergoing Laparoscopic Myomectomy. HeBei Med, 2020, 26(5): 751-754.
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2020, Vol. 26 
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