Abstract：Objective: To investigate the correlation between inflammatory cytokines in type 2 diabetes and cardiovascular and cerebrovascular diseases. Methods: From January 2018 to April 2019, 114 patients with type 2 diabetes admitted to our hospital were divided into two groups: the non combined group and the combined group, with 57 cases in each group. In addition, 57 outpatients were selected as the healthy group, All the selected persons were examined by carotid ultrasound to understand the pathological changes, and the levels of TNF - α, C-reactive protein, soluble intercellular adhesion molecule-1, soluble vascular cell adhesion molecule-1 and monocyte chemoattractant protein were detected by blood sampling. The results were analyzed and summarized. Results: The carotid intima thickening, the formation of carotid atherosclerotic plaque and the detection rate of carotid stenosis in the healthy group, the non combined group and the combined group were all gradually increased (P<0.05). The levels of TNF - α, C-reactive protein, soluble intercellular adhesion molecule-1, soluble vascular cell adhesion molecule-1 and monocyte chemoattractant protein in the healthy group, the non combined group and the combined group were gradually increased, and the difference was statistically significant (P<0.05). Conclusion: There is a correlation between the levels of inflammatory factors and cardiovascular and cerebrovascular diseases in type 2 diabetes. Inflammatory factors are risk factors for cardiovascular and cerebrovascular diseases in patients with type 2 diabetes.
2020, Vol. 26 
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