Abstract：Objective: To study the effects of levonorgestrel on the development of embryo or fetal, Methods: From July 2010 to January 2015, 78 cases of pregnancy taken levonorgestrel contraceptive failure and want to continue pregnancy were selected to be the study group, and at the same time, 78 cases of early pregnancy that want to continue pregnancy were selected as control group according to 1:1 matched. Analyze and compare the spontaneous abortion rate, the rate of fetal malformation and neonatal born. Results: Study group of spontaneous abortion rate was higher than that of the control group and had statistical significance (P < 0.05); the two groups in trisomy 21 and 18 trisomy and open neural tube malformation rate had no significant difference, do not have the statistical significance (P > 0.05); two groups of ultrasound screening for fetal malformation incidence had no significant difference, and were not statistically significant (P > 0.05); neonatal Apgar scores of the two groups had no significant difference, and had no the statistical significance (P > 0.05). Conclusion: The levonorgestrel could increase the chance of early spontaneous abortion; but the history of taking levonorgestrel did not increase trisomy 21, trisomy 18 and open neural tube malformation rate, fetal malformation rate and neonatal asphyxia incidence.
陈亚楠, 王娜. 左炔诺孕酮对胚胎胎儿发育的影响[J]. 河北医学, 2016, 22(10): 1632-1634.
CHEN Yanan, WANG Na. Effects of Levonorgestrel on Development of Embryo or Fetal. 河北医学, 2016, 22(10): 1632-1634.
2016, Vol. 22 
冀公网安备13080202000677号