Abstract：Objective: To explore the clinical effect of three different bone grafting methods in the treatment of lumbar degenerative diseases by TLIF. Methods: The clinical data of 109 patients with lumbar degenerative diseases who were treated by TLIF in Guangzhou General Hospital of Guangzhou Military Region from January 2012 to January 2016 were analyzed retrospectively. According to the fusion mode, they were divided into autoiliac bone + fusion cage (group A, 42 cases), autolaminar articular process bone + fusion cage (group B, 38 cases), allogeneic bone + fusion cage (Group C, 29 cases). The patients were followed up for 3 months, 6 months and 12 months. The operative indexes, fusion rate, VAS score of pain and JOA score of lumbar vertebrae were compared among the three groups. Results: There was no significant difference in operation time, intraoperative blood loss and hospital stay among the three groups (P>0.05). Three months after operation, the fusion rate of group A was higher than that of group B and group C, with statistical difference (P<0.05). There was no statistical difference in the fusion rate of 6 and 12 months after operation (P>0.05). Before operation, there was no significant difference in VAS and JOA scores among the three groups (P>0.05). At 3, 6 and 12 months after operation, the VAS scores of the three groups were lower than that before operation, and there was statistical difference between the three groups at 3 months after operation, but there was no statistical difference between the three groups at 6 and 12 months after operation (P>0.05); at 3, 6 and 12 months after operation, the JOA scores of the three groups were higher than that before operation, and there was no statistical difference between the three groups (P>0.05), and there was statistical difference between the two groups (P<0.05). Conclusion: TLIF is an effective method for the treatment of lumbar degenerative diseases. The short-term effect of the three methods is satisfactory. The interbody fusion rate of the autogenous ilium fusion group is better than that of the autogenous laminectomy fusion group and the allogeneic bone fusion group 3 months after the operation.
郑越生, 夏虹, 王智运, 区永亮. 三种不同植骨方法在TLIF手术治疗腰椎退变性疾病的临床研究[J]. 河北医学, 2020, 26(4): 639-644.
ZHENG Yuesheng, et al. Clinical Study of Three Different Bone Grafting Methods in the Treatment of Lumbar Degenerative Diseases with TLIF. HeBei Med, 2020, 26(4): 639-644.
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2020, Vol. 26 
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