Abstract：Objective: To evaluate the diagnostic value of CT detection in the diagnosis of patients with liver cirrhosis by referring to liver biopsypathological diagnosis. Methods: A total of 102 patients with chronic hepatitis B (CHB) admitted to the hospital from March 2018 to March 2019 were selected as the subjects. All of them underwent ultrasound-guided liver biopsy and CT detection. With the results of ultrasound-guided liver biopsy as the golden standard, the diagnostic value of CT detection in patients with liver cirrhosis was evaluated. Results: With the results of liver biopsy pathological diagnosis as the golden standard, the sensitivity, specificity, accuracy and Kappa value of CT detection for liver cirrhosis were 89.23% (58/65), 78.38% (29/37), 85.29% (87/102) and 0.680, respectively.Among the 65 patients with liver cirrhosis confirmed by liver biopsy pathology, CT found that 47.69%had abnormal liver morphology (including hepatic fissure widening and stiffness of liver surface contour), 49.23% had decreased liver CT value lower than that of the same level spleen, 40.00% had abnormal ratio of left to right liver lobe, 38.46% had portal vein outer diameter and spleen vein outer diameter widening, and 63.08% had splenomegaly. The overall coincidence rate of CT detection with liver biopsy pathological diagnosis for grade of liver function was 87.69%. CT signs of benign nodules of liver cirrhosis showed no obvious enhancement signal, but CT of malignant nodules showed a fast-in and fast-out enhancement mode, and the lesions became larger and more in a short time. Conclusion: CT detection is consistent with liver biopsy pathological diagnosis for early diagnosis of liver cirrhosis, evaluation of the severity and differential diagnosis of benign and malignant nodules. It may be an effective means for the diagnosis of liver cirrhosis.
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2020, Vol. 26 
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