Abstract：Objective: To explore the relationship between platelet volume distribution width, severity and prognosis in patients with stable coronary heart disease (SCAD) treated by PCI. Methods: From April 2015 to September 2017, 160 patients with stable coronary heart disease treated by PCI in our center were divided into two groups: group A (platelet volume distribution width ≤ 14.2%) and group B (platelet volume distribution width above 14.2%), 80 in each group. The results of angiography and biochemical indexes were collected, and the incidence of adverse events was compared. Results: Compared with patients in group A, the severity of coronary artery stenosis, lesion score and lesion number were significantly lower than those in group B (t=12.819, 6.707, 2.508, P<0.05). In addition, TG, LDL, TC and Cr in group A were significantly lower than those in group B (t=2.305, 4.476, 3.286, 2.741, P<0.05), while HDL was significantly higher than those in group B (t=2.280, P<0.05). In comparison with the prognosis, the incidence of total adverse events in group A was significantly lower than that in group B (χ2 =16.824, P<0.05). Conclusion: The higher the platelet volume distribution width of SCAD patients, the more serious the disease and the more adverse prognosis. And platelet volume distribution width is the sign of platelet activation and reliable. It is recommended that clinicians can be combined with platelet volume distribution width to assess patient's condition and prognosis.
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2019, Vol. 25 
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