Abstract：Objective: To compare the clinical efficacy of autologous platelet-rich gel (APG) and conventional dressing change in refractory diabetic foot (DF). Methods: 60 patients with refractory DF admitted to hospital from March 2017 to March 2019 were randomly divided into observation group (standard treatment+APG, n=30) and control group (standard treatment+conventional treatment, n=30). The treatment effects were compared between the two groups. Results: After 2 weeks, 4 weeks and 8 weeks of treatment, the ulcer area in the two groups was decreased in turn, and the difference between the two groups was significant (P<0.05), and the ulcer area in observation group after 2 weeks,4 weeks and 8 weeks of treatment was smaller than that in control group(P<0.05). The treatment effects in observation group were significantly better than those in control group(P<0.05). The ulcer healing time and hospital stay in observation group were significantly shorter than those in control group (P<0.05). During treatment, the incidence rate of adverse reactions in observation group was significantly lower than that in control group (P<0.05). Conclusion: APG combined with standard therapy can effectively improve the healing effect of ulcer in refractory DF patients.
2019, Vol. 25 
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