Abstract：Objective: To study the efficacy and safety of thoracic endovascular aortic repair (TEVAR) combined with drug and absolute drug therapy in patients with Stanford B type aortic dissection (Stanford B type AD). Methods: The clinical data of 86 patients with Stanford B type AD admitted to our hospital from2010.01 to 2015.01 were retrospectively analyzed. According to the treatment Methods, they were divided into combined group (TEVAR+drug therapy, n=56) and drug group (pure drug therapy, n=30). The treatment effects were observed in the two groups. Results: The success rate of surgical technique was 100% in combined group. There were no significant differences in the various complications during hospitalization between the two groups (P>0.05). There was no significant difference infatality rate during hospitalization (P>0.05). At 12~48 months of follow-up after operation, there were no significant differences in the fatality rate, major complications and maximum diameter of true lumen between the two groups (P>0.05), and the thrombosis formation rate and thrombus absorption rate in combined group were significantly higher than those in drug group (P>0.05), and the maximum diameter of false lumen was significantly less than that in drug group (P<0.05). The median survival time in drug group and combined group both were 48 months, and the Log Rank test showed there was no significant difference in survival rate between the two groups (χ2=0.50, P>0.05). Conclusion: TEVAR combined with drug therapy can effectively improve the thrombosis formation rate and thrombus absorption rate in patients with Stanford B type aortic dissection, and reduce the maximum diameter of false lumen. However, it has more postoperative complications and can not effectively extend the survival time of patients.
管军, 曾骞, 邓超. 胸主动脉夹层动脉瘤腔内修复术联合药物对稳定型B型主动脉夹层患者疗效及安全性研究[J]. 河北医学, 2019, 25(11): 1858-1861.
GUAN Jun, ZENG Qian, DENG Chao. Efficacy and Safety of Thoracic Endovascular Aortic Repair combined with Drug in Patients with Stanford B Type Aortic Dissection. HeBei Med, 2019, 25(11): 1858-1861.
2019, Vol. 25 
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