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河北医学  2019, Vol. 25 Issue (9): 1580-1584    DOI: 10.3969/j.issn.1006-6233.2019.09.046
  临床研究 本期目录 | 过刊浏览 | 高级检索 |
影响立体定向微创穿刺置管引流术患者急性期收缩压变异性增大的危险因素分析
冷晓丽, 李霖, 梁亚红
中国人民解放军西部战区空军医院神经外科, 四川 成都 610061
Analysis of Risk Factors Affecting the Increase of Systolic Blood Pressure Variability in Acute Phase in Patients with Stereotactic Minimally Invasive Puncture Catheter Drainage
LENG Xiaoli, LI Lin, LIANG Yahong
Chinese People's Liberation Army West War Zone Air Force Hospital, Sichuan Chengdu 610061, China
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摘要 目的:研究影响立体定向微创穿刺置管引流术患者急性期收缩压变异性(SBPV)增大的危险因素。方法:将医院2014年1月至2017年12月收治的200例行立体定向微创穿刺置管引流术的高血压脑出血(HICH)患者纳为研究对象,根据患者急性期SBPV是否增大将其分为SBPV增大组(n=102)与SBPV较小组(n=98),比较两组一般资料及血液生化指标,分析影响急性期SBPV增大的独立危险因素。结果:SBPV增大组与SBPV较小组性别、年龄、吸烟史、饮酒史、脑卒中史、糖尿病史、高血压史、规律服用降压药、脱水降压药使用情况间无显著性差异(P>0.05),两组入院时NIHSS评分、颅内血肿量及入院首次SBP值差异显著(P<0.05);SBPV增大组与SBPV较小组尿氮素、肌酐、总胆固醇、甘油三酯及载脂蛋白b水平存在显著性差异(P<0.05),两组低密度脂蛋白水平无显著性差异(P>0.05);经Logistic回归性分析提示,首次SBP、NIHSS评分、颅内血肿量及甘油三酯是立体定向微创穿刺置管引流术患者急性期SBPV增大的独立危险因素。结论:临床应积极监控入院时NIHSS评分较高及首次SBP水平较高者血压,做好降压处理,并建议高血压患者平时注意健康饮食,维持正常的血脂代谢,防止急性期SBPV增大。
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冷晓丽
李霖
梁亚红
关键词 立体定位微创穿刺置管引流术急性期收缩压变异性增大危险因素分析    
AbstractObjective:To study the risk factors for the increase of systolic blood pressure variability(SBPV)in acute phase in patients with stereotactic minimally invasive puncture catheter drainage. Methods: 200 patients with hypertensive intracerebral hemorrhage (HICH) who underwent stereotactic minimally invasive puncture catheter drainage in the hospital from January 2014 to December 2017 were included in the study.According to whether there was increased SBPV in acute phase, they were divided into increased SBPV group(n=102)and smaller SBPV group(n=98).The general data and blood biochemical indicators were compared between the two groups,and the independent risk factors affecting the increase of SBPV in acute phase were analyzed. Results: There were no significant differences between increased SBPV group and smaller SBPV group in terms of gender,age,smoking history,drinking history,history of stroke,history of diabetes,history of hypertension,regular use of antihypertensive drugs and dehydration and antihypertensive drugs(P>0.05),and there were significant differences in the NIHSS score and intracranial hematoma volume at admission and first SBP value at admission between the two groups(P<0.05).There were significant differences in the levels of urinary nitrogen,creatinine,total cholesterol,triglyceride and apolipoprotein between increased SBPV group and smaller SBPV group(P<0.05),and there was no significant difference in the level of low-density lipoprotein between the two groups(P>0.05).Logistic regression analysis indicated that the first SBP,NIHSS score,intracranial hematoma volume and triglyceride were independent risk factors for the increase of SBPV in acute phase of patients with stereotactic minimally invasive puncture catheter drainage. Conclusion: Clinically,the blood pressure of patients with higher NIHSS scores and higher SBP levels at admission should be actively monitored,and antihypertensive treatment should be done.It is recommended that patients with hypertension should pay attention to healthy diet,maintain normal lipid metabolism,and prevent the increase of SBPV in acute phase.
Key wordsStereotactic minimally invasive puncture catheter drainage    Increase of systolic blood pressure variability in acute phase    Risk factor analysis
    
基金资助:四川省卫生厅科研课题,(编号:112104658)
通讯作者: 李霖   
引用本文:   
冷晓丽, 李霖, 梁亚红. 影响立体定向微创穿刺置管引流术患者急性期收缩压变异性增大的危险因素分析[J]. 河北医学, 2019, 25(9): 1580-1584.
LENG Xiaoli, LI Lin, LIANG Yahong. Analysis of Risk Factors Affecting the Increase of Systolic Blood Pressure Variability in Acute Phase in Patients with Stereotactic Minimally Invasive Puncture Catheter Drainage. HeBei Med, 2019, 25(9): 1580-1584.
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