腹腔镜阑尾切除术对阑尾炎患者的疗效及对血清hs-CRP的影响

doi:10.3969/j.issn.1006-6233.2019.09.039

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摘要 目的:腹腔镜阑尾切除术对阑尾炎患者的疗效及对血清超敏C反应蛋白(hs-CRP)的影响。方法:选择2015年4月到2018年4月我院接诊的阑尾炎患者95例作为研究对象,以简单随机分组法分为观察组(n=50)和对照组(n=45),对照组使用开腹切除术,观察组采用腹腔镜切除术。比较两组手术时间、术后视觉模拟评分法(VAS)评分、住院时间、出血量、术后胃肠道恢复时间、hs-CRP水平、肿瘤坏死因子α(TNF-α)及术后不良反应发生情况。结果:观察组手术时间、术中出血量及术后VAS评分均显著低于对照组(P<0.05);治疗后,两组hs-CRP、TNF-α水平均明显改善;观察组优于对照组(P<0.05);观察组患者胃肠功能恢复时间均优于对照组(P<0.05);两组并发症总发生率为8.00%、28.89%,差异显著(P<0.05)。结论:在阑尾炎患者中应用腹腔镜阑尾切除术效果显著,对患者血清hs-CRP影响较小。

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	贺诗铭
	杨勇
	刘维政
	黄鑫

关键词 ：腹腔镜阑尾切除术, 阑尾炎, 超敏C反应蛋白

Abstract：Objective: To study the curative efficacy of laparoscopic appendectomy on appendicitis and its effectsonserum Hypersensitive c-reactive protein (hs-crp). Methods: 95 cases of patients with appendicitis treated in our hospital from April 2015 to April 2018 were selected as study objects,The patients were divided into observation group (n=50) and control group (n=45) according to the simple random number table method. The control group received laparotomy, while the observation group received laparoscopic resection. Operation time, postoperative visual analogue scale (VAS) score, hospital stay, blood loss, postoperative gastrointestinal recovery time, hs-crp level, tumor necrosis factor alpha (tnf-alpha) and postoperative adverse reactions were compared between the two groups. Results: The operation time, intraoperative blood loss and postoperative VAS score of the observation group were significantly lower than those of the control group (P<0.05). After treatment, the levels of hs-crp and tnf-alpha increased significantly in both groups. The levels of hs-crp and TNF- alpha in the observation group were significantly lower than those in the control group (P<0.05). The recovery time of bowel sound, anal exhaust time, anal defecation time and hospitalization time in the observation group were significantly lower than those in the control group (P<0.05). The total incidence of complications in the observation group was 8.00%, significantly lower than that in the control group (P<0.05). Conclusion: the application of laparoscopic appendectomy in patients with appendicitis has a significant effect and a small effect on serum hs-crp, which is worthy of promotion and application.

Key words： Laparoscopic appendectomy Appendicitis Hypersensitive c-reactive protein

基金资助:四川省自然科学基金资助项目,(编号:2013S025)

引用本文:

贺诗铭, 杨勇, 刘维政, 黄鑫. 腹腔镜阑尾切除术对阑尾炎患者的疗效及对血清hs-CRP的影响[J]. 河北医学, 2019, 25(9): 1552-1556.
HE Shiming, YANG Yong, LIU Weizheng, et al. Effect of Laparoscopic Appendectomy on Appendicitis and its Influence on Serum hs-CRP. HeBei Med, 2019, 25(9): 1552-1556.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2019.09.039 或 http://www.hbyxzzs.cn/CN/Y2019/V25/I9/1552

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