Curative Efficacy of Articular Cavity Injection of Sodium Lyaluronate and Ropivacaine combined with Arthroscopic Debridement in treatment of Osteoarthritis of the Knee
WU Ye,TAO Zhongliang, LI Jun, et al
Xuancheng People's Hospital, Anhui Xuancheng 242000, China
Abstract：Objective: To study curative efficacy of Articular cavity injection of sodium hyaluronate and ropivacaine combined with arthroscopic debridement in treatment of Osteoarthritis of the knee. Methods: 100 cases of knee osteoarthritis patients admitted to our hospital from February 2016 to February 2018 were selected as the research objects,randomized number table method was used to divide the observation group (n=51) and the control group (n=49). The control group was treated with arthroscopic debridement, and the observation group was treated with sodium hyaluronate injection and ropivacaine combined with arthroscopic debridement. After treatment, the efficacy, inflammatory indexes [interleukin-1 beta (il-1), tumor necrosis factor alpha (tnf-alpha), interleukin-6 (il-6)], knee joint function score (HSS), visualanalogue scale of pain (VAS), postoperative recovery time and quality of life of the two groups were compared. Results: After treatment, the excellent and good rates of patients in the two groups were 84.31% and 65.31% respectively, with statistically significant difference (P < 0.05). There was no significant difference in pre-treatment inflammatory index between the two groups. After treatment, the levels of inflammatory indexes in both groups were significantly decreased, and the levels of il-1 beta, tnf-alpha and il-6 in the observation group were significantly lower than those in the control group (P < 0.05). There was no significant difference in VAS and HSS scores between the two groups before treatment. After treatment, VAS score in both groups decreased significantly, and HSS score in the observation group was significantly higher than that in the control group, and VAS score was significantly lower than that in the control group (P < 0.05). After treatment, the postoperative recovery time of the observation group was significantly lower than that of the control group, and the quality of life score was significantly higher than that of the control group (P < 0.05). Conclusion: Intra-articular injection of sodium hyaluronate and ropivacaine combined with arthroscopic debridement in patients with knee osteoarthritis has a significant effect, which can effectively improve the knee function and inflammatory index level of patients, and is worthy of promotion and application.
吴晔, 陶忠亮, 李军, 王绍刚. 关节腔注射玻璃酸钠及罗哌卡因联合关节镜清理术对膝关节骨性关节炎的临床效果[J]. 河北医学, 2019, 25(9): 1539-1543.
WU Ye,TAO Zhongliang, LI Jun, et al. Curative Efficacy of Articular Cavity Injection of Sodium Lyaluronate and Ropivacaine combined with Arthroscopic Debridement in treatment of Osteoarthritis of the Knee. HeBei Med, 2019, 25(9): 1539-1543.
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2019, Vol. 25 
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