Abstract：Objective: To analyze the clinical characteristics of patients with Crohn's disease (CD) who underwent small intestine capsule endoscopy and the related factors of capsule retention and incompleteness. Methods: A retrospective study was conducted to collect clinical data of 106 CD patients who underwent small intestinal capsule endoscopy in our hospital. The clinical characteristics of the patients were recorded. The number of cases of capsule retention and incompleteness was counted. Multivariate logistic regression was used to analyze the influencing factors of capsule retention and incompleteness in small intestine capsule endoscopy. Results: Among 106 CD patients, 13 cases had not completed the small intestine capsule endoscopy, and the rate of incompleteness was 12.26%. Multivariate logistic regression analysis showed that gender, albumin, hemoglobin and diarrhea were related factors affecting the incompleteness of small intestinal capsule endoscopy in CD patients (P < 0.05). Among 106 CD patients, 6 cases were retained in small intestine capsule endoscopy, the retention rate was 5.66%. Of the 6 patients with capsule detention, 4 had no clinical symptoms (capsules were discharged by themselves after drug treatment), 2 had secondary intestinal obstruction (capsules were taken out by endoscopy). After symptomatic treatment, they were discharged smoothly. Conclusion: Gender, albumin, hemoglobin and diarrhea are all related factors affecting the incompleteness of small intestinal capsule endoscopy in CD patients. Before capsule endoscopy, we should pay close attention to the gastrointestinal motility and nutritional status of patients, exclude intestinal stricture, reduce the incomplete rate of examination as much as possible, and reduce the incidence of capsule retention.
黄妙兴, 李志坚, 刘宇虎, 戴映平, 徐明符. 行小肠胶囊内镜检查CD患者胶囊滞留和未完成的相关因素分析[J]. 河北医学, 2019, 25(9): 1503-1507.
HUANG Miaoxing, LI Zhijian, LIU Yuhu, et al. Analysis on Related Factors of Capsule Retention and Incomplete in Patients with CD by Small Intestine Capsule Endoscopy. HeBei Med, 2019, 25(9): 1503-1507.
[1] Rosa B, Pinho R, de Ferro SM, et al. Endoscopic scores for evaluation of crohn's disease activity at small bowel capsule endoscopy: General principles and current applications[J]. GE Port Gastroenterol,2015,23(1):36~41. [2] 冉志华,童锦禄.炎症性肠病诊断与治疗的共识意见(2018年,北京)克罗恩病部分解读[J].中华消化杂志,2018,38(5):315~317. [3] 杨静茹.腹部实时B超在诊断克罗恩病及其并发症中的应用[J].河北医学,2014,20(3):418~420. [4] 黄芳,盛红,薛世航,等.基层医院胶囊内镜对小肠钩虫病的诊断应用[J].中国基层医药,2015,22(20):3173~3174. [5] Kopylov U, Yung DE, Koulaouzidis A, et al. Retention rate in small-bowel capsule endoscopy[J]. Gastrointest Endosc,2017,86(3):573. [6] Garcia-Compeán D, González-Moreno EI. Video capsule retention in capsule endoscopy: How to prevent, diagnose, and manage that complication[J].Rev Gastroenterol Mex,2018,83(3): 361~362. [7] Kopylov U, Nemeth A, Koulaouzidis A, et al. Small bowel capsule endoscopy in the management of established Crohn's disease: clinical impact, safety, and correlation with inflammatory biomarkers[J]. Inflamm Bowel Dis,2015,21(1):93~100. [8] Du J, Pan D, Ma P, et al. The clinical characteristic and risk of capsule incomplete and retention in Crohn's disease[J]. Int Clin Exp Med,2015,8(8):13482~13490. [9] Kim Y, Jeon SR, Choi SM, et al. Practice patterns and clinical significance of use of capsule endoscopy in suspected and established Crohn's disease[J]. Intest Res,2017,15(4):467~474.
2019, Vol. 25 
冀公网安备13080202000677号