Abstract：Objective: To explore the effect of aspirin combined with edaravone on serum Hcy in patients with acute cerebral infarction. Methods: 70 patients with acute cerebral infarction who were treated in our hospital from March 2015 to December 2015 were selected as the research objects,the patients were divided into observation group (n=37) and control group (n=33) by random number table method. The control group was treated with aspirin, and the observation group was treated with edaravone on the basis of the control group. The clinical efficacy, serum Hcy, NIHSS score, modified Barthel index and the incidence of adverse reactions were compared between the two groups. Results: The total effective rate of the two groups was 94.59% and 69.70%, respectively (P < 0.05). After treatment, serum Hcy level in both groups was significantly decreased, and serum Hcy level in the observation group was significantly lower than that in the control group (P < 0.05). After treatment, NIHSS and improved Barthel index were significantly improved in both groups, and the improvement degree of NIHSS and improved Barthel index in the observation group was better than that in the control group (P < 0.05). The total incidence of adverse reactions in the two groups was 8.11% and 36.36%, with significant difference (P < 0.05). Conclusion:edaravone combined with aspirin in patients with acute cerebral infarction has a significant effect, which can improve the serum Hcy level of patients and improve the prognosis of patients with acute cerebral infarction, which is worthy of clinical promotion.
柯光敏, 鲍民强, 胡仁平. 阿司匹林联合依达拉奉对急性脑梗死患者血清Hcy的作用分析[J]. 河北医学, 2019, 25(9): 1477-1480.
KE Guangmin, BAO Minqiang, HU Renping. Effect Analysis of Aspirin Combined with Edaravone on Serum Hcy in Patients with Acute Cerebral Infarction. HeBei Med, 2019, 25(9): 1477-1480.
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2019, Vol. 25 
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